NCT04548531

Brief Summary

The goal of the study is to examine whether a shared decision making intervention improves decision making about colon cancer screening for patients who had their colonoscopy delayed or postponed due to the COVID pandemic. Eligible patients (n=800) will be randomly assigned to either the intervention or control arm. A subset will be surveyed about 6-8 weeks post intervention to measure shared decision making, their intention to follow through with screening, and their decisional conflict. Study staff will conduct medical chart review to track receipt of colon cancer screening within 6 months. The statistician will test whether patients in the intervention arm report more shared decision making, less decisional conflict, higher intention to follow through on screening and have higher screening rates compared to those in the control arm.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
800

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 9, 2020

Completed
1 day until next milestone

Study Start

First participant enrolled

September 10, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 14, 2020

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2021

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

February 22, 2023

Completed
Last Updated

February 22, 2023

Status Verified

May 1, 2022

Enrollment Period

8 months

First QC Date

September 9, 2020

Results QC Date

April 13, 2022

Last Update Submit

May 19, 2022

Conditions

Keywords

Shared Decision MakingColon Cancer ScreeningCOVID-19

Outcome Measures

Primary Outcomes (1)

  • Shared Decision Making (SDM) Process Scale Score

    short patient reported scale asks patients about discussion of options, pros and cons of colonoscopy and discussion of patients' preferences. Total scores range from 0-4 with higher scores indicating higher shared decision making.

    About 8 weeks after intervention

Secondary Outcomes (4)

  • No Decisional Conflict (Number With Score of 4 on SURE Scale)

    About 8 weeks after intervention

  • Patient's Preferred Approach to Screening

    About 8 weeks after intervention

  • Number Reporting "Very Likely" to Follow Through With Screening

    About 8 weeks after intervention

  • Colon Cancer Screening Rate

    6 months after randomization

Study Arms (2)

Usual Care Arm

NO INTERVENTION

This arm will be a usual care arm. Patients may call to schedule a colonoscopy or other tests as desired.

Shared Decision Making Arm

EXPERIMENTAL

This is the intervention arm. Patients will receive a shared decision making information sheet in the mail and will be able to receive decision coaching from study staff to support selection of an option if desired.

Behavioral: Shared Decision Making

Interventions

The decision aid is a paper information sheet presenting the pros and cons of three screening options (colonoscopy, stool-based tests, and postponing cancer screening until next year). The decision coaching is a structured interview to help patients clarify their preference for screening test and to support them in implementation (whether scheduling colonoscopy, ordering stool test or seeking additional advice from specialist).

Also known as: Decision aid, Decision coaching
Shared Decision Making Arm

Eligibility Criteria

Age45 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adults, age 45-75
  • Had screening or surveillance colonoscopy delayed or cancelled from March-June 2020

You may not qualify if:

  • Diagnostic colonoscopy
  • High risk for colorectal cancer as indicated by 1 year follow up schedule
  • Prior history of colon cancer
  • Unable to read or write in English or Spanish
  • Have already scheduled or completed a colonoscopy since restrictions were lifted

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

Location

MeSH Terms

Conditions

Colonic NeoplasmsCOVID-19

Interventions

Decision Support Techniques

Condition Hierarchy (Ancestors)

Colorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal DiseasesPneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Investigative Techniques

Results Point of Contact

Title
Karen Sepucha
Organization
Massachusetts General Hospital

Study Officials

  • Karen Sepucha, PhD

    Massachusetts General Hospital

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Patients will not be given any information on their assigned arm. Statistician will be blinded to the assignment when analyzing the results.
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Model Details: Two-armed randomized control trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director of Health Decision Sciences Center

Study Record Dates

First Submitted

September 9, 2020

First Posted

September 14, 2020

Study Start

September 10, 2020

Primary Completion

April 30, 2021

Study Completion

April 30, 2021

Last Updated

February 22, 2023

Results First Posted

February 22, 2023

Record last verified: 2022-05

Data Sharing

IPD Sharing
Will share

Yes To promote research replicability, transparency and future use of the data, de-identified data sets of the patient survey data will be created and will be available, by request, to outside researchers. After the main manuscripts have been published, de-identified data sets will also be deposited in an open access service such as, ICPSR (https://www.icpsr.umich.edu/icpsrweb/). Before a dataset is made available for access, ICPSR completes a detailed review of all datasets to assess disclosure risk. If necessary, ICPSR modifies data to reduce disclosure risk or limits access to datasets for which modifying the data would substantially limit their utility or the risk of disclosure remains high. No information that contains identifiers or that could be used to link an individual to the data will be included in the de-identified data set.

Shared Documents
STUDY PROTOCOL, SAP, ANALYTIC CODE
Time Frame
Three months after the end of the funded grant period, the study materials and de-identified data will be available, by request, from the PI. Once data are placed on an open access service such as ICPSR they will be available indefinitely.
Access Criteria
The PI will share a de-identified data set with outside investigators at no cost, according to approved Partners and Massachusetts General Hospital policies for data sharing. Investigators from other sites will be able to request the data and will be required to complete a data use agreement that ensures that all local Institutional Review Board requirements are met before using the data, that they will not attempt to identify any data in the dataset, and that they will not share the data set with anyone outside their project team. On ICPSR, individuals must register and agree to ICPSR's Responsible Use statement prior to accessing datasets.

Locations