NCT04548037|Terminated
Study Stopped
Departure of the principal investigator
Assessment of Emotional Memory During Transient Global Amnesia
EMOTICTUS
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Sponsor study identifier
observational
2
1 country
1
Study Start
May 30, 2022
Actual (reported)Primary Completion
June 12, 2023
Actual (reported)Study Completion
June 12, 2023
Actual (reported)There are few studies on the role played by emotions in transient global amnesia (TGA), in particular with regard to their impact on the functioning of memory. The study investigators wish to better understand the link between episodic memory, emotional state and psychogenic factors during TGA. It would be interesting to see if the patients suffering from TGA triggered by a psychological shock process emotional information differently from those whose TGA was triggered by an "organic" shock (physical effort, trauma, etc.). Finally, amnesic stroke is a good model for better understanding the function of the hippocampus, in particular of the CA1 region, in episodic memory.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 12, 2023
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 4, 2020
Actual (reported)September 14, 2020
Actual (reported)May 30, 2022
Actual (reported)June 12, 2023
Actual (reported)June 12, 2023
Actual (reported)Storage and retrieval capacities of information with a strong emotional valence in patients compared to healthy controls
International Affective Picture System (IAPS): number of correctly memorized images of each type of emotional content (15 positive, 15 negative and 15 neutral).
Day 0
Ability to judge the degree of activation and emotional value associated with images
Self Assessment Manikin (SAM)
Day 0
Change in storage and retrieval capacities of information with a strong emotional valence in patients from baseline
Day 3
Change in storage and retrieval capacities of information with a strong emotional valence in patients from baseline
Month 3
Classification of event triggering transient global amnesia
Day 0
Anxiety
Day 0
Depression
Day 0
The subject is placed in supine position, the head immobilized in a headrest. The imaging sequence begins with a scout view (viewing angle 90 °, 120 kV, 20 mA), then an X-ray scan is performed for the attenuation correction (120 kV, 5 mAs per slice, pitch 0.531, collimation 40 mm , FOV 70) and diagnostic CT scan (120 kV, 100-250 mA: auto mA, pitch 0.531, 40 MM, DFOV 25, ASIR 60%, thickness 1.25 mm). Finally, the positron emission tomography is acquired: static in 3D mode for 15 minutes, 30 minutes after the injection of 18 FDG, the axial field of view is 25, the matrix in 256 x 256, OSEM reconstruction 6 iterations 24 subsets, attenuation correction, diffused, and PSF. Gaussian filter, cutoff frequency of 4. Obtaining forty-seven contiguous sections of 3.26 mm thick.
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Adult patients with a transient global amnesia according to the criteria of Hodges and Warlow (1990) in the acute phase (i.e. within 24 hours after the onset of the stroke), accompanied by a trusted person and admitted to the SAU of the CHU de Nîmes, plus a group of healthy volunteers.
CHU de Nimes
Nîmes, France
Eric THOUVENOT
CHU Nimes
2 participants (actual enrollment reported by the registry).
First Submitted
September 4, 2020
First Posted
September 14, 2020
Study Start
May 30, 2022
Actual (reported)Circulating Tumor Cell Detection in Patients With Luminal A Breast Cancer
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Primary Completion
June 12, 2023
Actual (reported)Study Completion
June 12, 2023
Actual (reported)Last Updated
February 8, 2024
Record last verified: 2024-01
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Source: ClinicalTrials.gov.
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