NCT04547595

Brief Summary

The purpose of this study is to determine whether hypnosis intervention added to usual care is more effective than usual care alone to control pain during lavage procedure in patients with knee osteoarthrosis

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at below P25 for phase_3 knee-osteoarthritis

Timeline
Completed

Started Oct 2021

Longer than P75 for phase_3 knee-osteoarthritis

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 7, 2020

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 14, 2020

Completed
1.1 years until next milestone

Study Start

First participant enrolled

October 6, 2021

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2025

Completed
Last Updated

December 30, 2024

Status Verified

December 1, 2024

Enrollment Period

3.5 years

First QC Date

September 7, 2020

Last Update Submit

December 26, 2024

Conditions

Keywords

hypnosis interventionanalgesicsknee osteoarthritisjoint lavage

Outcome Measures

Primary Outcomes (1)

  • Pain assessed by Visual Analog Scale

    VAS range 0-10, 10 for most severe pain

    One Day, at end of lavage procedure

Secondary Outcomes (7)

  • Anxiety assessed by Visual Analog Scale

    Day 1, before lavage procedure

  • Anxiety assessed by Visual Analog Scale

    Day 1, at end of lavage procedure

  • Pain assessed by Visual Analog Scale

    Day 1, before lavage procedure

  • Pain assessed by Visual Analog Scale

    Day 7, after lavage procedure

  • Gesture tolerability

    Day 1, at end of lavage procedure

  • +2 more secondary outcomes

Study Arms (2)

CONTROL

NO INTERVENTION

Standard care

Hypnosis

ACTIVE COMPARATOR

Standard care + intervention

Other: Hypnosis

Interventions

given by Expert in this method

Also known as: Ericksonienne Method
Hypnosis

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • diagnosis of knee osteoarthritis
  • indication for a lavage

You may not qualify if:

  • People who have had both knees washed on the same day.
  • People who have already received a joint lavage.
  • Patients with psychotic disorders.
  • Refusal to participate.
  • People who do not understand and/or speak French or who are deaf.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cochin Hospital - Rheumatology department

Paris, 75014, France

RECRUITING

MeSH Terms

Conditions

Osteoarthritis, Knee

Interventions

Hypnosis

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Anna MOLTO, MD, PhD

    APHP

    STUDY CHAIR

Central Study Contacts

Melissa CREHALET MONNIER, Nurse

CONTACT

Guillaume MASSON, MSc

CONTACT

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 7, 2020

First Posted

September 14, 2020

Study Start

October 6, 2021

Primary Completion

April 1, 2025

Study Completion

April 1, 2025

Last Updated

December 30, 2024

Record last verified: 2024-12

Data Sharing

IPD Sharing
Will not share

Locations