Associations Between Pain Perceptions and Movement-evoked Pain.

NCT04545853 | Withdrawn

• 1 other identifier: MEP_PC
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to investigate the associations between pain cognitions and movement-evoked pain in people with musculoskeletal pain complaints.

Conditions

Musculoskeletal Pain

Outcome Measures

Primary Outcomes (6)

• Movement-evoked pain

  Pain that is experienced in response to a physical task. Participants will perform a lifting task. Participants will be asked to lift a series of 19-canisters that will be arranged in a standardized pattern on a waist-high table. Participants will provide a pain rating on a 11 points Numeric Rating Scale (NRS) with the endpoints no pain" (0) and "excruciating pain" (10)

  Assessed only once at baseline.

• Illness perceptions

  The illness perception questionnaire-revised (IPQ-R) will be used to measure patients' illness perceptions. In the first domain, called illness identity, the perceived symptoms and their possible relation to the illness are evaluated. In this study, participants will indicate whether or not they believe that a specific symptom is related to pain ("yes" or "no"). The second domain, the beliefs domain, covers 7 dimensions: the acute/chronic timeline, the cyclical character of the illness, the consequences, controllability, curability, emotional representations and illness coherence. The third domain lists 18 possible causes to which individuals attribute their condition, the degree to which individuals perceive themselves as responsible for the illness, as well as the responsibility individuals take for curing themselves. For each item in the second and third domain, patients rate their level of agreement on a 5-point Likert scale, ranging from "strongly disagree" to "strongly agree"

  Assessed only once at baseline

• Pain catastrophizing

  The Pain Catastrophizing Scale (PCS) is a questionnaire to objectify catastrophic thinking about pain. It consists of 13 items describing different thoughts and feelings that individuals may have when experiencing pain. Items are scored on a 5-point scale. A general score and scores on 3 subscales (i.e., helplessness (6 items), magnification (3 items), and rumination (4items)) will be obtained; higher scores indicate more severe catastrophic thoughts about pain

  Assessed only once at baseline

• Attention to pain

  The Pain Vigilance and Awareness Questionnaire (PVAQ) will be used to investigate patients' attention to pain. It is a 16-item measure of attention to pain that assesses awareness, consciousness, vigilance, and observation of pain. Scores range from 0 to 80 and high scores correspond to hypervigilance for pain.

  Assessed only once at baseline

• Fear of injury due to movement

  The Tampa Scale for Kinesiophobia (TSK) is a 17-item questionnaire that will be used to measure the fear of (re) injury due to movement. Scores range from 17 to 68, with scores ≤ 37 suggesting low fear of movement and scores \> 37 indicating high fear of movement.

  Assessed only once at baseline

• Quality of life, an individual's perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns.

  The 36-item short form health survey (SF-36) is a multidimensional generic questionnaire assessing quality of life, which consists of 8 dimensions: physical functioning (10 items), role constraint caused by physical health problems (4 items), bodily pain (2 items), general health (5 items), vitality (4 items), social functioning (2 items), role constraint caused by emotional problems (3 items) and mental health (5 items). Higher scores reflecting a better health condition

  Assessed only once at baseline

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Participants will be recruited by flyers at the University Hospital Brussels, social media. Prior to inviting the eligible participants, the presence of musculoskeletal pain will be confirmed by phone in order to proceed to the informed consent process. Musculoskeletal pain is defined as pain, that potential participants report, feeling in the muscles, joints or bones. This pain can be localized, regional, or widespread.

You may qualify if:

• years or older,
• presence of musculoskeletal pain for more than three months,
• medically stable (no serious health conditions, no pending surgery or invasive medical procedure, no contraindication to physical activity).

You may not qualify if:

• Presence of co-existing pain conditions of other origins with chronic musculoskeletal pain not being the primary condition (i.e. predominant subject of symptom complaints)
• severe underlying comorbidity (like diagnosed diabetes, cardiovascular problems, etc.)
• pregnant or given birth in the preceding year.

Sponsors & Collaborators

• Vrije Universiteit Brussel: lead

MeSH Terms

Conditions

Musculoskeletal Pain

Condition Hierarchy (Ancestors)

Muscular Diseases; Musculoskeletal Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: September 4, 2020
• First Posted: September 11, 2020
• Study Start: October 1, 2020
• Primary Completion: May 15, 2021
• Study Completion: June 1, 2021
• Last Updated: January 3, 2022

Record last verified: 2021-12