NCT04545073

Brief Summary

To compare the prediction error of ORA vs formula for post-LASIK cataract patients when PanOptix IOL was implanted. Using post-operative outcomes to determine if preoperative IOL calculations, including Barrett TK, Barrett Universal II, Hill RBF, ASCRS post-refractive calculator, or intraoperative aberrometry is more accurate when the two methods disagree in patients who have had previous refractive surgery undergo cataract surgery.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 21, 2020

Completed
20 days until next milestone

First Posted

Study publicly available on registry

September 10, 2020

Completed
29 days until next milestone

Study Start

First participant enrolled

October 9, 2020

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2021

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2021

Completed
Last Updated

October 19, 2020

Status Verified

October 1, 2020

Enrollment Period

5 months

First QC Date

August 21, 2020

Last Update Submit

October 15, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • To determine if preoperative IOL calculations or intraoperative aberrometry is more accurate when the two methods disagree in patients who have had previous refractive surgery undergo cataract surgery.

    1. Percentage of eyes within +/- .5D of target for each formula and ORA. 2. Overall % of eyes that have a disagreement between the two methods

    Pre-op to 9 month visit

Secondary Outcomes (7)

  • Post-operative monocular visual acuity

    3 to 9 month visit

  • Post-operative best corrected visual acuity

    3 to 9 month visit

  • Post-operative uncorrected visual acuity

    3 to 9 month visit

  • Post-operative visual acuity

    3 to 9 month visit

  • Post-operative visual acuity

    3 to 9 month visit

  • +2 more secondary outcomes

Study Arms (1)

Post-refractive trifocal IOL

Device: PanOptix

Interventions

PanOptixDEVICE

Trifocal IOL with ORA in post refractive patients

Post-refractive trifocal IOL

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Charts from up to 200 myopic post-refractive patients who have received PanOptix will be reviewed at at least two Vance Thompson Vision sites (Fargo, ND and Sioux Falls, SD). All patients will have had ORA used during the cataract surgery.

You may qualify if:

  • Previous myopic refractive surgery
  • At least 3 months post op cataract surgery with a trifocal IOL

You may not qualify if:

  • Pre-existing or subsequent eye condition that interferes with accurate data collection (retinal detachment, etc.)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Vance Thompson Vision ND

West Fargo, North Dakota, 58078, United States

RECRUITING

MeSH Terms

Conditions

Refractive Errors

Condition Hierarchy (Ancestors)

Eye Diseases

Study Officials

  • Michael Greenwood, MD

    Vance Thompson Vision ND

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 21, 2020

First Posted

September 10, 2020

Study Start

October 9, 2020

Primary Completion

March 1, 2021

Study Completion

May 1, 2021

Last Updated

October 19, 2020

Record last verified: 2020-10

Locations