NCT04534413

Brief Summary

Accessing nodules located in the most outer part of the lung is challenging. Tissue that will be removed from the lung will be used to see if we can reach and see the nodule with a very small camera. This camera that may reach in the smaller and outer airways is called a composite optical fiberscope (COF). The purpose of this study is to evaluate insertion ability of the COF and visualization of the lung tumor by the COF. In order to do so, we plan to evaluate 50 patient samples from the University Health Network over the span of 2 years.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
16mo left

Started Aug 2020

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress82%
Aug 2020Dec 2027

Study Start

First participant enrolled

August 5, 2020

Completed
21 days until next milestone

First Submitted

Initial submission to the registry

August 26, 2020

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 1, 2020

Completed
7.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 5, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 5, 2027

Last Updated

May 1, 2026

Status Verified

April 1, 2026

Enrollment Period

7.3 years

First QC Date

August 26, 2020

Last Update Submit

April 27, 2026

Conditions

Lung Cancer

Outcome Measures

Primary Outcomes (1)

  • insertion ability of the COF using human ex-vivo lungs

    3 years

Interventions

composite optical fiberscope (COF)DEVICE

Fiber Technology

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Any patients scheduled for lobectomy or anatomical segmental resection for malignant lung tumors

You may qualify if:

  • Any patients scheduled for lobectomy or anatomical segmental resection for malignant lung tumors.
  • years of age or older.

You may not qualify if:

  • \) Any patients with inability to give informed consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Toronto General Hospital

Toronto, Ontario, M5G 1L7, Canada

Location

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Kazuhiro Yasufuku

Study Record Dates

First Submitted

August 26, 2020

First Posted

September 1, 2020

Study Start

August 5, 2020

Primary Completion (Estimated)

December 5, 2027

Study Completion (Estimated)

December 5, 2027

Last Updated

May 1, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations

CA(1)