Alveolar Ridge Sequelae Due to Peri-implantitis: a Retrospective Observational Study

NCT04534361 | Completed DMC

• 1 other identifier: SES-CEI-120820
• Study Type: observational
• Target: 26
• Locations: 1 country
• Sites: 1

Brief Summary

The scientific evidence available at present regarding the alterations suffered by the alveolar ridge after the explantation of implants that have been considered to be abandoned due to periimplantitis, as well as the remaining sequelae from said treatment, is scarce and inconclusive. Regarding this background, it is speculated that the different types of peri-implant defects present different bone remodeling and different sequelae after the explantation of the implants affected by peri-implantitis. Thus, it has been hypothesized that the peri-implant defect configuration has an influence on the radiographic bone alterations that occur after explantation. In order to test this hypothesis, a retrospective study has been designed as it follows: Patients who have undergone implant placement procedure and suffer from peri-implantitis will be consecutively included in the study. In addition, patients should present at least 2 CBCTs taken before and after explantation, 4-6 months apart. Linear measurements will be taken in order to assess dimensional changes of the alveolar ridge at 1, 3, 5 and 7 mm from the bone crest.

Conditions

Dental Implant; Peri-Implantitis; Bone Remodeling

Keywords

dental implant; dental implant failure; peri-implantitis; bone loss; bone remodeling; implant explantation

Outcome Measures

Primary Outcomes (1)

• bone level changes

  bone level changes (mm) and peri-implant defect morphology alterations after implant explantation

  4-6 months after implant explantation

Interventions

CBCT measurements OTHER

No intervention will be performed on patients for this study. Based on the CBCTs already done previously of the patients in the sample, linear measurements will be taken in order to assess dimensional changes of the alveolar ridge at 1, 3, 5 and 7 mm from the bone crest in the CBCTs taken before and after implant explantation, 4-6 months apart.

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient recruitment will be obtained from a private practice exclusively dedicated to periodontics and implantology (Clinica CICOM, Badajoz, Spain). Edentulous patients, either total or partial, who previously underwent implant placement procedure and which suffer severe peri-implantitis will be consecutively included in the study.

You may qualify if:

• patients aged 18-80 years
• patients with partial or complete edentulism with ≥1 missing teeth restored with implant-supported restorations
• patients with implants which had been in function for a minimum of 36 months after final prosthesis delivery
• patients presenting implant explantation due to peri-implantitis

You may not qualify if:

• pregnancy or lactation patients
• patients treated by zygomatic or pterygoid implants
• patients under intake of medications known to modify bone metabolism
• patients with uncontrolled systemic diseases (ie: diabetes mellitus)
• patients with active periodontal disease that required treatment

Sponsors & Collaborators

• Universitat Internacional de Catalunya: lead

Study Sites (1)

Universitat Internacional de Catalunya

Sant Cugat del Vallès, Barcelona, 08195, Spain

Location

Related Publications (1)

• Pons R, Carreno M, Amerio E, Gargallo-Albiol J, Nart J, Monje A. Hard tissue dimensional changes following implant removal due to peri-implantitis: A retrospective study. Clin Implant Dent Relat Res. 2021 Jun;23(3):432-443. doi: 10.1111/cid.13004. Epub 2021 May 4.

  PMID: 33949080 DERIVED

MeSH Terms

Conditions

Peri-Implantitis; Bone Diseases, Metabolic

Condition Hierarchy (Ancestors)

Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Jose Nart

  Universitat Internacional de Catalunya

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dentistry, Master in Periodontics and Implants

Study Record Dates

• First Submitted: August 26, 2020
• First Posted: September 1, 2020
• Study Start: August 15, 2020
• Primary Completion: August 30, 2020
• Study Completion: September 1, 2020
• Last Updated: November 19, 2021

Record last verified: 2021-11

Locations

ES (1)