NCT04533334

Brief Summary

Pediatric patients are exposed to increased risk during general anesthesia. A myriad of problems can be encountered in the pediatric population by misplaced endotracheal tubes. Especially, during one-lung ventilation (OLV) a right-sided or left-sided tube is inserted to facilitate the surgery. However, inadvertent tube use, caused by misinterpretation of the distances of the trachea and the main bronchi, may cause unintended hypoxemia, postoperative atelectasis and even mortality. In this study, investigators will measure the distance between distal margin of right lung upper lobe orifice-carina and carina-lip with the help of fiberoptic bronchoscopy (FOB).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
299

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 9, 2019

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

August 26, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 31, 2020

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 9, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 9, 2021

Completed
Last Updated

May 3, 2023

Status Verified

May 1, 2023

Enrollment Period

2 years

First QC Date

August 26, 2020

Last Update Submit

May 1, 2023

Conditions

Keywords

anesthesiafiberoptic bronchoscopylower airway anatomychildright upper lobe bronchus

Outcome Measures

Primary Outcomes (1)

  • Upper/Lower Airway Ratio

    Ratio of the distance between labium oris to carina and carina to right upper lobe orifice

    1 day

Secondary Outcomes (1)

  • Correlation between patient characteristics and distances measured by FOB

    1 day

Study Arms (1)

Pediatric

FOB measurement of the distance between carina and right upper lobe bronchus and carina and labium oris in pediatric population

Procedure: FOB measurement

Interventions

A FOB will be inserted after anesthesia induction and the distances will be measured by direct observation via the bronchoscope.

Pediatric

Eligibility Criteria

Age1 Year - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

All patients undergoing general anesthesia via an endotracheal tube will be eligible for recruitment.

You may qualify if:

  • All patients undergoing general anesthesia via an endotracheal tube
  • ASA I-III

You may not qualify if:

  • Patients that do not meet age criteria
  • Uncontrolled asthma or hyper reactive airway
  • hypoxemia, previous thoracic surgery
  • ASA \> III
  • Unstable hemodynamics
  • Patients with tracheal or oral malignancies
  • Patients with face trauma
  • Informed consent not given
  • using a tube with a number too small for the fiberoptic bronchoscope to pass through

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istanbul University-Cerrahpasa

Istanbul, 34098, Turkey (Türkiye)

Location

Related Publications (1)

  • Rudraraju P, Eisen LA. Confirmation of endotracheal tube position: a narrative review. J Intensive Care Med. 2009 Sep-Oct;24(5):283-92. doi: 10.1177/0885066609340501. Epub 2009 Aug 3.

    PMID: 19654121BACKGROUND

Study Officials

  • PINAR Kendigelen, MD

    Istanbul University - Cerrahpasa

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

August 26, 2020

First Posted

August 31, 2020

Study Start

January 9, 2019

Primary Completion

January 9, 2021

Study Completion

January 9, 2021

Last Updated

May 3, 2023

Record last verified: 2023-05

Locations