NCT04533191

Brief Summary

The objective of this investigator initiated study (IIT-001) is to obtain data on clinical methods which can be used during the examination of patients desiring binocular custom vision with the Light Adjustable Lens (LAL). An analysis of the collected data will be performed to determine whether these clinical assessments can be used by doctors to enhance their patient's clinical outcome.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 25, 2020

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 31, 2020

Completed
1 day until next milestone

Study Start

First participant enrolled

September 1, 2020

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2021

Completed
Last Updated

May 20, 2024

Status Verified

May 1, 2024

Enrollment Period

4 months

First QC Date

August 25, 2020

Last Update Submit

May 16, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • Binocular uncorrected distance, intermediate, and near visual acuity

    Through Month one post-op

  • Binocular uncorrected depth of focus

    Through Month one post-op

Secondary Outcomes (5)

  • Manifest refraction

    Through Month one post-op

  • Monocular uncorrected distance visual acuity

    Through Month one post-op

  • Monocular best corrected distance visual acuity

    Through Month one post-op

  • Visual Satisfaction

    Through Month one post-op

  • 4th order total eye spherical aberration (Z12)

    Through Month one post-op

Study Arms (1)

Subjects treated with LAL lens

Subjects that underwent standard of care cataract surgery and LAL IOL placement.

Procedure: LAL IOL lens

Interventions

LAL IOL lensPROCEDURE

Standard of care Cataract surgery with IOL placement

Subjects treated with LAL lens

Eligibility Criteria

Age18 Years - 110 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

A population of 25 patients who plan to undergo bilateral cataract surgery with implantation of commercially available Light Adjustable Lens (LAL) and receive binocular custom vision.

You may qualify if:

  • Patients able to sign informed consent
  • Patients who plan to undergo bilateral implantation with the commercial LAL and receive binocular custom vision are eligible for study participation.

You may not qualify if:

  • Inability to sign informed consent
  • Any pathology for which, in the investigator's judgement, could reduce the subjects BCVA
  • Unable to return for light treatments

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Vance Thompson Vision

Sioux Falls, South Dakota, 57108, United States

Location

MeSH Terms

Conditions

CataractPseudophakia

Condition Hierarchy (Ancestors)

Lens DiseasesEye DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 25, 2020

First Posted

August 31, 2020

Study Start

September 1, 2020

Primary Completion

January 1, 2021

Study Completion

February 1, 2021

Last Updated

May 20, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will not share

Locations