NCT04532359

Brief Summary

The primary objective is to describe the evolution of implant stability between the date of implant placement and 3 months later when the implant is implementated in patients treated for cancer of the upper aero-digestive tract

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Feb 2021

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 26, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 31, 2020

Completed
5 months until next milestone

Study Start

First participant enrolled

February 5, 2021

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2023

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2024

Completed
Last Updated

October 15, 2021

Status Verified

October 1, 2021

Enrollment Period

2.8 years

First QC Date

August 26, 2020

Last Update Submit

October 14, 2021

Conditions

Keywords

Upper aero-digestive tract CancerDental implant placement

Outcome Measures

Primary Outcomes (1)

  • Evolution of implant stability in patients treated for cancer of the upper aero-digestive tract between placement and 3 months after placement

    Measure with Osstell Beacon device (Implant Stability Quotient : value from 1 to 100)

    At 3 months after implant placement

Secondary Outcomes (2)

  • Evaluation of the association between the type of bone (maxilla/mandible and fibula) and implant stability

    At 3 months after implant placement

  • Evaluation of the correlation between the irradiation dose received at the implant site and implant stability

    At 3 months after implant placement

Interventions

Implant placement

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with squamous cell carcinoma of the upper aero-digestive tract (oral cavity, oropharynx, hypopharynx) who are going to undergo a surgical intervention with placement of dental implant(s) in an irradiated area or in the microanastomosis fibula flap.

You may qualify if:

  • Patient with squamous cell carcinoma of the upper aero-digestive tract (oral cavity, oropharynx, hypopharynx
  • Patient having been treated by external radiotherapy and/or having benefited from a microanastomosis fibula flap
  • Patient going to undergo a surgical intervention with placement of dental implant(s) in an irradiated area or in the microanastomosis fibula flap
  • Non-opposition to the study

You may not qualify if:

  • Patient having difficulties speaking and understanding French
  • Patient under tutorship or curatorship

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre Léon Bérard

Lyon, 69008, France

RECRUITING

MeSH Terms

Conditions

Neoplasms

Study Officials

  • Anne-Gaëlle CHAUX-BODARD, MD

    Centre Leon Berard

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 26, 2020

First Posted

August 31, 2020

Study Start

February 5, 2021

Primary Completion

December 1, 2023

Study Completion

March 1, 2024

Last Updated

October 15, 2021

Record last verified: 2021-10

Locations