Utility and Validity of a High-intensity, Intermittent Exercise Protocol

NCT04531891 | Completed

• 1 other identifier: BC-07679
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to identify an exercise-induced fatigue protocol to mimic central and peripheral acute fatigue effects associated with participation in vigorous dynamic sports activities and to understand the expected central (cardiovascular) and peripheral (muscular) impact of this protocol.

Conditions

Fatigue

Outcome Measures

Primary Outcomes (8)

• Heart rate

  Heart rate, expressed in beats per minute

  This parameters will be continuously monitored 10 minutes before the start of the fatigue protocol until 30 minutes after completion of the protocol

• Isokinetic dynamometry

  Isokinetic dynamometry of the quadriceps muscle

  This parameter will be monitored 10 minutes before the start of the fatigue protocol

• Isokinetic dynamometry

  Isokinetic dynamometry of the quadriceps muscle

  This parameter will be monitored immediately after completion of the protocol

• Isokinetic dynamometry

  Isokinetic dynamometry of the quadriceps muscle

  This parameter will be monitored 15 minutes after completion of the protocol

• Isokinetic dynamometry

  Isokinetic dynamometry of the quadriceps muscle

  This parameter will be monitored 30 minutes after completion of the protocol

• Blood lactate level

  Blood lactate level, expressed in millimol per liter

  This parameters will be monitored 10 minutes before the start of the fatigue protocol

• Blood lactate level

  Blood lactate level, expressed in millimol per liter

  This parameters will be monitored 10 minutes after completion of the protocol

• BORG

  BORG-score, indicating the rate of perceived exertion for legs and breathlessness

  This parameters will be continuously monitored 10 minutes before the start of the fatigue protocol until 30 minutes after completion of the protocol

Secondary Outcomes (1)

• Circuit time

  Time will be recorded immediately after completion of the fatigue protocol

Study Arms (2)

All-out, high-intensity, intermittent exercise protocol

EXPERIMENTAL

Other: Fatigue protocol

5 min, high-intensity, intermittent exercise protocol

EXPERIMENTAL

Other: Fatigue protocol

Interventions

Fatigue protocol OTHER

During the fatigue protocol, participants will sprint forward 5 m, cut at a 90° angle, sprint forward another 5 m, and backpedal 5 m. This activity will be repeated 4 times before participants will complete a series of hurdle activities. First, they will perform 2-legged jumps over 5 hurdles that are 30 cm high, turn, and repeat the jumps. Second, they will perform side-stepping exercises over the 5 hurdles. Third, they will complete four 5-m lateral shuffles.

5 min, high-intensity, intermittent exercise protocol; All-out, high-intensity, intermittent exercise protocol

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Men
• ≥ 18 years
• Volley- and basketball, non-elite
• ≥ 3 times per week sports participation
• No acute or overuse low back/lower extremity injuries in the past 6 months

You may not qualify if:

• Women
• \<18 years
• \>45 years
• other sports than volley- and basketball
• elite players
• \<3 times per week sports participation
• acute or overuse low back/lower extremity injuries in the past 6 months

Sponsors & Collaborators

• University Ghent: lead

Study Sites (1)

Vakgroep Revalidatiewetenschappen

Ghent, Oost-Vlaanderen, 9000, Belgium

Location

MeSH Terms

Conditions

Fatigue

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: SCREENING
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Each participant will randomly be assigned to two different fatigue protocols, on separate days. The first protocol is a high-intensity, intermittent exercise protocol and will be performed until complete exhaustion. The second protocol is a time-based variant of the previous protocol and will be performed during 5 minutes.

Study Record Dates

• First Submitted: August 13, 2020
• First Posted: August 31, 2020
• Study Start: September 7, 2020
• Primary Completion: June 30, 2021
• Study Completion: November 19, 2021
• Last Updated: November 22, 2021

Record last verified: 2021-11

Locations

BE (1)