NCT04525248

Brief Summary

Study the recurrence rate of constipation after laparoscopic total colectomy with high resection or low resection of rectum

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
78

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2020

Longer than P75 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 18, 2020

Completed
7 days until next milestone

First Posted

Study publicly available on registry

August 25, 2020

Completed
7 days until next milestone

Study Start

First participant enrolled

September 1, 2020

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2023

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2024

Completed
Last Updated

August 25, 2020

Status Verified

August 1, 2020

Enrollment Period

2.9 years

First QC Date

August 18, 2020

Last Update Submit

August 23, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • 1-year recurrence rate of constipation

    1-year recurrence rate of constipation

    1 year

Secondary Outcomes (2)

  • 1-year rate of diarrhea

    1 year

  • perioperative complications

    1 year

Study Arms (2)

High resection

ACTIVE COMPARATOR

Laparoscopic total colectomy + High resection of rectum

Procedure: Laparoscopic total colectomy + High resection of rectum

Low resection

EXPERIMENTAL

Laparoscopic total colectomy + Low resection of rectum

Procedure: Laparoscopic total colectomy + low resection of rectum

Interventions

Laparoscopic total colectomy + low resection of rectum

Low resection

Laparoscopic total colectomy + High resection of rectum

High resection

Eligibility Criteria

Age15 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosed as constipation according to Rome IV criteria
  • Diagnosed as slow transit constipation
  • With more than 2 years' drug treatment or with outlet obstruction or with surgical history

You may not qualify if:

  • Colon cancer
  • History of colon, rectum, anus surgery
  • With severe cardio, renal, neural disease
  • Pregnant patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Constipation

Condition Hierarchy (Ancestors)

Signs and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Minhua Zheng

    Shanghai MISC

    STUDY CHAIR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 18, 2020

First Posted

August 25, 2020

Study Start

September 1, 2020

Primary Completion

August 1, 2023

Study Completion

August 1, 2024

Last Updated

August 25, 2020

Record last verified: 2020-08

Data Sharing

IPD Sharing
Will not share