NCT04523155

Brief Summary

The purpose of this study is to evaluate the effect of medically-tailored meal delivery (10 meals per week for 3 months) on glycemic control in diabetic patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
34

participants targeted

Target at P25-P50 for not_applicable type-2-diabetes

Timeline
Completed

Started Aug 2020

Shorter than P25 for not_applicable type-2-diabetes

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 19, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 21, 2020

Completed
3 days until next milestone

Study Start

First participant enrolled

August 24, 2020

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 4, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 4, 2021

Completed
Last Updated

July 12, 2021

Status Verified

July 1, 2021

Enrollment Period

9 months

First QC Date

August 19, 2020

Last Update Submit

July 9, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in Glucose Metabolism

    Measured by HbA1c levels in standard chemistry in blood

    Baseline, 3 monts

Secondary Outcomes (5)

  • Change in Weight

    Baseline, 3 months

  • Change in Blood Pressure

    Baseline, 3 months

  • Change in High Density lipoprotein (HDL)

    Baseline, 3 months

  • Change in Low Density Lipoprotein (LDL)

    Baseline, 3 months

  • Change in Triglycerides

    Baseline, 3 months

Study Arms (2)

Treatment Sequence AB

EXPERIMENTAL

Participants randomized to sequence AB will receive 3 months of meals, followed by a 3 month washout period and a 3 month intervention period with no meals.

Dietary Supplement: Medically tailored meals

Treatment Sequence BA

EXPERIMENTAL

Participants randomized to sequence BA will receive 3 months of no meals followed by a 3 month washout period and a 3 month intervention period with meals.

Dietary Supplement: Medically tailored meals

Interventions

Medically tailored mealsDIETARY_SUPPLEMENT

10 meals per week for 3 months

Treatment Sequence ABTreatment Sequence BA

Eligibility Criteria

Age25 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult men and women with non-insulin dependent diabetes.
  • Ages 25 to 75 years.
  • Fasting blood sugar of greater than 140 mg/dl, on no oral hypoglycemic agents and a hemoglobin A1C less than 13%.
  • Stabilized patients on oral hypoglycemic agents for one month or longer prior to starting the study and a hemoglobin A1C between 7.5% - 13%.

You may not qualify if:

  • Insulin use.
  • Substance abuse.
  • Any documented medical problem that would inhibit full participation in the study.
  • BMI less than 25 or great than 40.
  • Vegans or Vegetarians
  • Individuals with food allergies.
  • Individuals currently on a commercial weight loss or diet program.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Mayo Clinic in Florida

Jacksonville, Florida, 32224, United States

Location

Mayo Clinic

Jacksonville, Florida, 32224, United States

Location

Related Links

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Bryan Farford, DO

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

August 19, 2020

First Posted

August 21, 2020

Study Start

August 24, 2020

Primary Completion

June 4, 2021

Study Completion

June 4, 2021

Last Updated

July 12, 2021

Record last verified: 2021-07

Data Sharing

IPD Sharing
Will not share

Locations