NCT04519060

Brief Summary

The eyes of hospitalized infants are often assessed by dilated exam, and there is evidence that infants experience post-exam stress. Investigators will evaluate whether eye shields for infants after dilated eye exam lessen stress and discomfort.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
106

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 17, 2020

Completed
3 months until next milestone

First Posted

Study publicly available on registry

August 19, 2020

Completed
6 months until next milestone

Study Start

First participant enrolled

February 1, 2021

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2021

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2021

Completed
Last Updated

March 12, 2021

Status Verified

March 1, 2021

Enrollment Period

8 months

First QC Date

May 17, 2020

Last Update Submit

March 10, 2021

Conditions

Keywords

eye shieldeye protectoreye patcheye maskphototherapy

Outcome Measures

Primary Outcomes (1)

  • Number of stress events

    The primary outcome will be measured by the count of apneas and bradycardias (stress events) experienced by the infant during the period of eye dilation without eye shields as compared to the total stress events experienced when dilated eyes are covered with eye shields.

    4-6 hours (from first dose of eye dilating medication to four hours after last dose)

Secondary Outcomes (1)

  • Number of stress events amongst covariates

    4-6 hours (from first dose of eye dilating medication to four hours after last dose)

Study Arms (2)

No eye shields after dilated eye exam

NO INTERVENTION

Eye dilation for scheduled exam will be followed by routine clinical care.

Eye shields after dilated eye exam

EXPERIMENTAL

Eye dilation for scheduled exam will be followed by routine clinical care and the application of eye shields. They will be worn until four (4) hours after the last dose of dilating eye drops.

Device: phototherapy eye shield

Interventions

Phototherapy eye shields will be applied to the eyes of infants dilated for scheduled eye exam. They will be worn until four (4) hours after the last dose of dilating eye drops.

Also known as: phototherapy eye protector, phototherapy eye mask
Eye shields after dilated eye exam

Eligibility Criteria

AgeUp to 1 Year
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Chronological age 0-12 months
  • Infants who require dilated eye exams
  • Parent or legal guardian consent/permission granted

You may not qualify if:

  • More than a two-week interval between dilated eye exams
  • Prior or ongoing medical treatment or therapy for the eye(s)
  • Functional blindness diagnosed by eye exam

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Children's Hospital Los Angeles

Los Angeles, California, 90027, United States

RECRUITING

MeSH Terms

Conditions

DiseasePainRetinopathy of PrematurityEye Diseases

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and SymptomsNeurologic ManifestationsSigns and SymptomsRetinal DiseasesInfant, Premature, DiseasesInfant, Newborn, DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

Maxine Ogbaa, BSN

CONTACT

Heidi Machen, PHN, BSN

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
BSN

Study Record Dates

First Submitted

May 17, 2020

First Posted

August 19, 2020

Study Start

February 1, 2021

Primary Completion

October 1, 2021

Study Completion

December 1, 2021

Last Updated

March 12, 2021

Record last verified: 2021-03

Data Sharing

IPD Sharing
Will not share

Locations