Quality of Life of Patients Over 75 Yars Undergoing Palliative Chemotherapy

NCT04517448 | Terminated

• 1 other identifier: P-2020/01
• Study Type: observational
• Target: 31
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this research is to evaluate the quality of life of patients over 75 years of age undergoing palliative chemotherapy for digestive cancer. It is a non-interventional study that evaluates the quality of life before and after a cycle of chemotherapy with a composite criterion including: a standardized questionnaire "Cancer specific quality of Life questionnaire" (QLQC30), an assessment of autonomy by "Activity of daily living" questionnaire (ADL), and the number of days of hospitalization.

Conditions

Colorectal Cancer; Pancreatic Cancer; Biliary Cancer; Hepatic Cancer; Oesophageal Cancer; Gastric Cancer

Keywords

Digestive cancer, age other 75 years old, palliative therapy, quality of life

Outcome Measures

Primary Outcomes (1)

• Change in the response scores to the standardized questionnaire Quality of life questionnaire in cancer patient

  The primary outcome is a composite criterion comparing the response scores to the standardized questionnaire Quality of life in cancer patient . These data will be collected during the first inpatient chemotherapy course in hospitalization and during the last chemotherapy before evaluation. A higher score would mean a worsening of the situation

  Before first chemotherapy and at Month 3 of chemotherapy

Secondary Outcomes (1)

• Change in the Activity of daily living score

  Before first chemotherapy and at Month 3 of chemotherapy

Eligibility Criteria

• Age: 75 Years+
• Sex: all
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient other 75 years old, undergoing a palliative chemotherapy for a digestive cancer : colorectal, pancreatic, biliary, oesophageal, gastric, proved by histology, whatever the histologic type (adenocarcinoma, epidermoid carcinoma, neuroendocrine carcinoma); at a palliative stage (not resecable, multimetastatic) and who will perform a first course of palliative chemotherapy.

You may qualify if:

• Age over 75 years old
• Suffering from digestive cancer : colorectal, pancreatic, biliary, oesophageal, gastric
• Palliative cancer : not resectable, multimetastatic
• Decision in multi-disciplinary liaising meeting (CPR) to perform a first course of palliative chemotherapy
• Having received an informed consent form
• Understanding french language

You may not qualify if:

• Cognitive disorders
• Patient benefiting from a legal protection measure
• Life expectancy below 1 year
• Not understanding french language

Sponsors & Collaborators

• Centre Hospitalier de la côte Basque: lead

Study Sites (1)

CH Côte Basque

Bayonne, 64109, France

Location

MeSH Terms

Conditions

Colorectal Neoplasms; Pancreatic Neoplasms; Biliary Tract Neoplasms; Liver Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Gastrointestinal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases; Endocrine Gland Neoplasms; Pancreatic Diseases; Endocrine System Diseases; Biliary Tract Diseases; Liver Diseases; Head and Neck Neoplasms; Esophageal Diseases; Stomach Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: August 14, 2020
• First Posted: August 18, 2020
• Study Start: October 16, 2020
• Primary Completion: October 23, 2021
• Study Completion: November 23, 2021
• Last Updated: September 26, 2024

Record last verified: 2024-09

Locations

FR (1)