NCT04500093

Brief Summary

Total hip arthroplasty (THA) has been successful in relieving pain and restoring function in patients with advanced arthritis of the hip joint. Increased focus on earlier recovery and decreased postoperative pain has improved overall satisfaction. However, there is still a gap between the clinical scores in objective surveys and patient satisfaction. Direct anterior approach total hip arthroplasty has a low dislocation rate, abductor strength restoration, acceleration, and cosmetic advantages. In this method, capsulotomy with repair or capsulectomy is applied as the preferences of surgeons. Therefore, this can cause both a decrease in hip flexion strength and a loss in knee extension strength. Our aim in this study is to reveal how much muscle loss was caused by comparing both methods with the intact side.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2020

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 1, 2020

Completed
1 day until next milestone

Study Start

First participant enrolled

August 2, 2020

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 5, 2020

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2022

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2022

Completed
Last Updated

August 5, 2020

Status Verified

August 1, 2020

Enrollment Period

2.1 years

First QC Date

August 1, 2020

Last Update Submit

August 1, 2020

Conditions

Keywords

HipArthroplastyQuadriceps strenghtMuscle WeaknessKneeFlexionExtension

Outcome Measures

Primary Outcomes (1)

  • Muscle Weakness

    Newton

    1 year

Secondary Outcomes (1)

  • Harris Hip Score

    1 year

Study Arms (2)

Capsulotomy with Repair

EXPERIMENTAL

Repair after capsulotomy in direct anterior hip arthroplasty

Procedure: Capsulotomy with Repair

Capsuloectomy

ACTIVE COMPARATOR

Capsuloectomy in direct anterior hip arthroplasty

Procedure: Capsuloectomy

Interventions

Capsulotomy with Repair

Capsulotomy with Repair
CapsuloectomyPROCEDURE

Capsuloectomy

Capsuloectomy

Eligibility Criteria

Age45 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All primary THA

You may not qualify if:

  • Secondary THA

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bezmialem Vakif University

Istanbul, Fatih, 34000, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Osteoarthritis, HipMuscle Weakness

Interventions

Wound Healing

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesMuscular DiseasesNeuromuscular ManifestationsNeurologic ManifestationsNervous System DiseasesPathologic ProcessesPathological Conditions, Signs and SymptomsSigns and Symptoms

Intervention Hierarchy (Ancestors)

RegenerationBiological Phenomena

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, Resident Doctor in Orthopaedic Surgery

Study Record Dates

First Submitted

August 1, 2020

First Posted

August 5, 2020

Study Start

August 2, 2020

Primary Completion

August 30, 2022

Study Completion

November 30, 2022

Last Updated

August 5, 2020

Record last verified: 2020-08

Data Sharing

IPD Sharing
Will share
Shared Documents
STUDY PROTOCOL, SAP

Locations