Pulsed Electromagnetic Field Therapy Versus Transcutaneous Electrical Nerve Stimulation in on Post-herpetic Neuralgia of the Sciatic Nerve

NCT04488835 | Completed

• 1 other identifier: 68mm
• Study Type: interventional
• Target: 52
• Locations: 1 country
• Sites: 1

Brief Summary

Background and purpose: Post-herpetic neuralgia (PHN) is the most frequent chronic complication of herpes zoster, resulting in post- infectious severe neuropathic pain. Due to drug resistance severe pain; patients with PHN suffer from reduced physical activities, social and psychological manifestations as well as decrease in the quality of life. The purpose of this research was to evaluate the efficacy of pulsed electromagnetic field therapy (PEMFT) versus transcutaneous electrical nerve stimulation (TENS) in the treatment of post-herpetic neuralgia of the sciatic nerve. Methods: In an eight weeks period of treatemnt, 52 patients were randomly and equally assigned into two groups. Both groups received conventional physical therapy treatment protocol. Moreover, group (A) has an additional TENS application and group (B) had PEMFS application. TENS and the PEMFT were applied once daily, three times per week for 20 minutes for each session. Assessment performed pre and post intervention using visual analogue scale (VAS) and estimation of the carbamazepine intake (CMI).

Conditions

Neuralgia,Postherpetic

Outcome Measures

Primary Outcomes (1)

• neuralgia

  Visual analogue scale for pain ,zero indicates no pain ten indicates maximum pain

  8 weeks

Study Arms (2)

TENS Therapy Group

EXPERIMENTAL

patients in this group received TENS therapy in addition to routine physical therapy

Other: Electromagnetic field therapy and transcutaneous electrical nerve stimulation

PEMFT group

EXPERIMENTAL

patients in this group received PEMFT therapy in addition to routine physical therapy

Other: Electromagnetic field therapy and transcutaneous electrical nerve stimulation

Interventions

Electromagnetic field therapy and transcutaneous electrical nerve stimulation OTHER

Both groups received conventional physical therapy treatment protocol. Moreover, group (A) has an additional TENS application and group (B) had PEMFS application. TENS and the PEMFT were applied once daily, three times per week for 20 minutes for each session. Assessment performed pre and post intervention using visual analogue scale (VAS) and estimation of the carbamazepine intake (CMI).

PEMFT group; TENS Therapy Group

Eligibility Criteria

• Age: 30 Years - 40 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age from 30-40 years
• History of herpes zoster more than 90 days
• Visual analogue scale is greater than or equal 5 out on a scale from 0 to 10
• All patients were on pain medication "Carbamazepine"

You may not qualify if:

• uncooperative behavior
• Intellectual disability to complete the self-evaluation questionnaires

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Marwa Eid

Cairo, 2011, Egypt

Location

MeSH Terms

Conditions

Neuralgia, Postherpetic

Interventions

Transcutaneous Electric Nerve Stimulation

Condition Hierarchy (Ancestors)

Neuralgia; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Electric Stimulation Therapy; Therapeutics; Physical Therapy Modalities; Rehabilitation; Analgesia; Anesthesia and Analgesia

Study Officials

• Marwa Eid, Ass.prof.

  Cairo University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor of physical therapy for surgery

Study Record Dates

• First Submitted: July 22, 2020
• First Posted: July 28, 2020
• Study Start: March 10, 2018
• Primary Completion: March 20, 2019
• Study Completion: October 15, 2019
• Last Updated: August 13, 2020

Record last verified: 2020-08

Locations

EG (1)