Lung Ultrasound in COVID-19 Patients
LUS-COVID
Early Lung Ultrasound Score Predicts Duration of Ventilation and ICU Mortality in COVID-19 Invasively Ventilated Patients
1 other identifier
observational
137
1 country
1
Brief Summary
To assess the prognostic performance of an early global LUS score with respect to the mortality in ICU and duration of ventilation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jun 2020
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2020
CompletedFirst Submitted
Initial submission to the registry
July 24, 2020
CompletedFirst Posted
Study publicly available on registry
July 27, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2020
CompletedJuly 31, 2024
July 1, 2024
7 months
July 24, 2020
July 29, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Liberation from invasive ventilation
Patient who survived but remained invasively ventilated up to day 28 were marked without event. Patients who survived but were extubated were marked with an event at the day of successful extubation.
28 days
Secondary Outcomes (1)
Mortality
28 days
Eligibility Criteria
Severe COVID-19 infection under invasive ventilation who received lung ultrasound examination as a standard care.
You may qualify if:
- Admitted to an ICU participating in this study between February 1, 2020 and April 30, 2020
- Confirmed with reverse transcriptase polymerase chain reaction (RT-PCR) COVID-19 infection
- Having had received invasive ventilation
- Having had examined at least once with lung ultrasound under invasive ventilation
You may not qualify if:
- Age \<18 years
- First examination with LUS in patients already under extracorporeal membrane oxygenation (ECMO) support.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Amsterdam, Netherlands
Related Publications (1)
Pierrakos C, Lieveld A, Pisani L, Smit MR, Heldeweg M, Hagens LA, Smit J, Haaksma M, Veldhuis L, Schmidt RW, Errico G, Marinelli V, Attou R, David CE, Zimatore C, Murgolo F, Grasso S, Mirabella L, Cinnella G, De Bels D, Schultz MJ, Tuinman PR, Bos LD. A Lower Global Lung Ultrasound Score Is Associated with Higher Likelihood of Successful Extubation in Invasively Ventilated COVID-19 Patients. Am J Trop Med Hyg. 2021 Oct 18;105(6):1490-1497. doi: 10.4269/ajtmh.21-0545.
PMID: 34662857DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Marcus J Schultz, MD
Amsterdam University Medical Centers, location 'AMC'
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Prof. M.J. Schultz, MD, PhD
Study Record Dates
First Submitted
July 24, 2020
First Posted
July 27, 2020
Study Start
June 1, 2020
Primary Completion
December 31, 2020
Study Completion
December 31, 2020
Last Updated
July 31, 2024
Record last verified: 2024-07