NCT04486599

Brief Summary

The aim of this study is to evaluate the feasibility of assisted electromagnetic navigation in percutaneous echo-guided sclerotherapy of slow-flow vascular malformations. Feasibility will be defined in terms of the percentage of patients for whom the procedure is successful.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2020

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 9, 2020

Completed
6 days until next milestone

Study Start

First participant enrolled

July 15, 2020

Completed
9 days until next milestone

First Posted

Study publicly available on registry

July 24, 2020

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 12, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 12, 2022

Completed
Last Updated

February 22, 2023

Status Verified

February 1, 2023

Enrollment Period

1.8 years

First QC Date

July 9, 2020

Last Update Submit

February 21, 2023

Conditions

Keywords

Foam SclerotherapyUltrasoundElectromagnetic Navigation

Outcome Measures

Primary Outcomes (1)

  • Percentage of patients for whom the procedure is successful

    Success of procedure a.e. obtention of venous flow at the extremity of the needle permitting the realization of the foam sclerotherapy treatment.

    day 1

Secondary Outcomes (3)

  • Estimate the number of punctures required to achieve catheterization of the malformation.

    day 1

  • Estimate the time to complete catheterization of the malformation

    day 1

  • Estimate the undesirable effects associated with assisted electromagnetic navigation.

    day 1

Study Arms (1)

Electromagnetic Navigation

EXPERIMENTAL

The patient have to low Flow Vascular Abnormality diagnosed by Duplex Ultrasound and MRI. Decision of Ultrasound Guided Percutaneous Foam Sclerotherapy taken in multidisciplinary staff meeting

Device: Electromagnetic Navigation

Interventions

The echo-guided sclerotherapy procedure, assisted by electromagnetic navigation, will be carried out in a clean room during the day hospitalisation and followed by a control Echo-Doppler carried out 2 hours after the procedure.

Electromagnetic Navigation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Low Flow Vascular Abnormality diagnosed by Duplex Ultrasound and MRI
  • Decision of Ultrasound Guided Percutaneous Foam Sclerotherapy taken in multidisciplinary staff meeting

You may not qualify if:

  • patients with pacemakers or internal defibrillator
  • patients with ferromagnetic implanted material
  • patients who are wards of court or under guardianship
  • patients deprived of freedom by judicial or administrative decision
  • patients under legal protection
  • pregnant women

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital

Toulouse, Occitanie, 31059, France

Location

Study Officials

  • Wassim Mokaddem, MD

    University Hospital, Toulouse

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 9, 2020

First Posted

July 24, 2020

Study Start

July 15, 2020

Primary Completion

May 12, 2022

Study Completion

May 12, 2022

Last Updated

February 22, 2023

Record last verified: 2023-02

Locations