Comparison of Two Methods of Transnasal Sphenopalatine Ganglion Block

NCT04479176 | Completed

• 1 other identifier: AJIRB-MED-MDB-20-565
• Study Type: observational
• Target: 74
• Locations: 1 country
• Sites: 1

Brief Summary

The transnasal sphenopalatine ganglion block(SPGB) is administered to patients with facial or head and neck pain. In the transnasal approach, the drip and topical methods are frequently used. We compared facial temperatures and VAS after transnasal SPGB.

Conditions

Sphenopalatine Ganglion Block

Outcome Measures

Primary Outcomes (2)

• Facial temperatures

  Facial temeratures changes after transnasal SPGB

  Before, and 30 minutes after completion of transnasal sphenopalatine ganglion block

• Visual analogue scale(VAS)

  11 points pain scale score from 0 to 10

  Before, and 30 minutes after completion of transnasal sphenopalatine ganglion block

Study Arms (2)

Drip-method group

Transnasal SPGB was performed by a single pain clinician. After the patient was placed in a supine and neck-extended position, 2 mL of 2% mepivacaine was placed in a syringe connected to a 16-gauge Angiocath sheath. The sheath of the Angiocath was inserted through the nostril, and 2% mepivacaine was dripped into the nostrils with the patient in a supine position. The mepivacaine drip on the nasal pharynx was maintained for 10 min. A drip of 2% mepivacaine was delivered to the nostril, where the pain was dominant. In cases of bilateral pain, mepivacaine drip was administered to both nostrils.

Procedure: Transnasal Sphenopalatine Ganglion Block

Topical-method group

Transnasal SPGB was performed by a single pain clinician. The posture was the same as that in the drip method. A cotton tip applicator soaked with 2% mepivacaine was inserted vertically into the nostril. After the cotton tip applicator made contact with the posterior wall of the middle turbinate, the cotton tip applicator was fixed for 10 min. A cotton tip applicator was inserted into the nostril, where the pain was dominant. In cases of bilateral pain, two applicators were inserted into both nostrils.

Procedure: Transnasal Sphenopalatine Ganglion Block

Interventions

Transnasal Sphenopalatine Ganglion Block PROCEDURE

In transnasal approach, several authors described the traditional technique using sterile 10cm cotton tipped applicators that are dipped in the chosen anesthetic and then advanced along the superior border of the middle turbinate, until it reaches the posterior wall of the nasopharynx. Some other techniques had described dripping one or two ml of the anesthetics into the nostril.

Drip-method group; Topical-method group

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The patients who visited pain clinic of Ajou university hospital, and a total of 74 patients who be performed transnasal sphenopalatine ganglion block

You may qualify if:

• (1) age over 20 years ; (2) head and neck pain; (3) pain score \> 4 on the VAS in the head and neck; and (4) having undergone a transnasal SPGB and having had facial temperatures measured.

You may not qualify if:

• (1) patients with a history of head and neck surgery, (2) treatment with a vasodilator or vasoconstrictor, (3) contraindication to treatment using a transnasal approach, (4) clinically significant systemic disease or any reduced organ failure, and (5) missing data.

Sponsors & Collaborators

• Ajou University School of Medicine: lead

Study Sites (1)

Ajou University Hospital

Suwon, Gyunggi, 16499, South Korea

Location

Study Officials

• Kim

  Ajou University School of Medicine

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: July 15, 2020
• First Posted: July 21, 2020
• Study Start: March 10, 2021
• Primary Completion: October 1, 2021
• Study Completion: October 1, 2021
• Last Updated: October 20, 2021

Record last verified: 2021-10

Data Sharing

• IPD Sharing: Will not share

Locations

KR (1)