NCT04474990

Brief Summary

Primary Objective: To treat a single patient with gastroparesis who has requested expanded access with tradipitant

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

15 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 13, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 17, 2020

Completed
Last Updated

August 24, 2025

Status Verified

August 1, 2025

First QC Date

July 13, 2020

Last Update Submit

August 18, 2025

Conditions

Keywords

gastroparesisidiopathicdiabetictradipitantnauseavomitingstomachmotilityfunctionalNK-1 antagonistneurokinin 1 receptorsubstance pexpanded access

Interventions

NK-1 Receptor antagonist

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Identified subject who requested expanded access
  • Diagnosed with gastroparesis
  • Demonstrated delayed gastric emptying
  • Presence of moderate to severe nausea
  • Patient does not qualify for or does not have access to other clinical trials with tradipitant;

You may not qualify if:

  • Another active disorder or treatment which could explain or contribute to symptoms of gastroparesis
  • A positive test for drugs of abuse at the screening or evaluation visits;
  • Exposure to any investigational medication in the past 60 days other than tradipitant
  • Gastrectomy, fundoplication, vagotomy, pyloroplasty, bariatric surgery, or gastric stimulation device surgically implanted within the last year
  • Any other reason as determined by the Investigator which may lead to an unfavorable risk-benefit ratio to treatment;

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (15)

Vanda Investigational Site

Maitland, Florida, 32751, United States

AVAILABLE

Vanda Investigational Site

Tampa, Florida, 33613, United States

AVAILABLE

Vanda Investigational Site

Wauconda, Illinois, 60084, United States

AVAILABLE

Vanda Investigational Site

Wichita, Kansas, 67214, United States

AVAILABLE

Vanda Investigational Site

Louisville, Kentucky, 40202, United States

AVAILABLE

Vanda Investigational Site

Chevy Chase, Maryland, 20815, United States

AVAILABLE

Vanda Investigational Site

Boston, Massachusetts, 02215, United States

AVAILABLE

Vanda Investigational Site

Chesterfield, Missouri, 63005, United States

AVAILABLE

Vanda Investigational Site

Charlotte, North Carolina, 28209, United States

AVAILABLE

Vanda Investigational Site

Tulsa, Oklahoma, 74104, United States

AVAILABLE

Vanda Investigational Site

Philadelphia, Pennsylvania, 19104, United States

AVAILABLE

Vanda Investigational Site

Nashville, Tennessee, 37211, United States

AVAILABLE

Vanda Investigational Site

Houston, Texas, 77084, United States

AVAILABLE

Vanda Investigational Site

Plano, Texas, 75024, United States

AVAILABLE

Vanda Investigational Site

Spokane, Washington, 99202, United States

AVAILABLE

MeSH Terms

Conditions

GastroparesisNauseaVomiting

Condition Hierarchy (Ancestors)

Stomach DiseasesGastrointestinal DiseasesDigestive System DiseasesParalysisNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsSigns and Symptoms, Digestive

Central Study Contacts

Vanda Pharmaceuticals

CONTACT

Study Design

Study Type
expanded access
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 13, 2020

First Posted

July 17, 2020

Last Updated

August 24, 2025

Record last verified: 2025-08

Locations