Intraretinal Cystoid Changes After Vitrectomy With Membrane Peeling

NCT04472039 | Completed

• 1 other identifier: RAC
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Aim of the study is to assess the rate of postoperative intraretinal cystoid changes after pars plana vitrectomy with membrane peeling and peribulbar application of triamcinolone acetonide and to examine possible risk factors for postoperative intraretinal cystoid changes.

Conditions

Macular Edema, Cystoid

Outcome Measures

Primary Outcomes (1)

• Intraretinal cystoid changes

  presence of intraretinal cystoid changes in OCT is assessed during the time period of 3 months after surgery

  3 months

Secondary Outcomes (2)

• intraocular pressure (IOP)

  3 months

• distance corrected visual acuity

  3 months

Study Arms (1)

Studygroup

Retrospective analysis of OCT, IOP and distance corrected visual acuity from the patients history.

Device: optical coherence tomography (OCT)

Interventions

optical coherence tomography (OCT) DEVICE

OCT visualizes the retinal layers by backreflection of light

Studygroup

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients having undergone pars plana vitrectomy with membrane peeling and periocular application of triamcinolone acetonide at the end of surgery between June 2019 and January 2020 at the department of Ophthalmology of the Hanusch Hospital in Vienna, Austria, were selected for the study

You may qualify if:

• presence of an ERM
• indication for membrane peeling defined as significant loss of vision and/or metamorphopsia due to the ERM
• application of periocular triamcinolone acetonide at the end of surgery
• at least one follow-up examination present in the patient's history

You may not qualify if:

• macular edema caused by conditions other than ERM (such as choroidal neovascularization, diabetic macular edema, etc.)

Sponsors & Collaborators

• Vienna Institute for Research in Ocular Surgery: lead

Study Sites (1)

Vienna Institute for Research in Ocular Surgery (VIROS), Hanusch Hospital Vienna

Vienna, 1140, Austria

Location

MeSH Terms

Conditions

Macular Edema

Interventions

Tomography, Optical Coherence

Condition Hierarchy (Ancestors)

Macular Degeneration; Retinal Degeneration; Retinal Diseases; Eye Diseases

Intervention Hierarchy (Ancestors)

Tomography, Optical; Optical Imaging; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Tomography; Investigative Techniques

Study Officials

• Oliver Findl, Prof.

  Vienna Institute for Research in Ocular Surgery

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof. Dr. Oliver Findl, MBA

Study Record Dates

• First Submitted: July 11, 2020
• First Posted: July 15, 2020
• Study Start: June 30, 2020
• Primary Completion: September 28, 2020
• Study Completion: September 28, 2020
• Last Updated: September 29, 2020

Record last verified: 2020-09

Locations

AU (1)