Worldwide Trends on COVID-19 Research After the Declaration of COVID-19 Pandemic

NCT04460547 | Unknown DMC

• 1 other identifier: COAHS
• Study Type: observational
• Target: 200
• Locations: 0 countries
• Sites: N/A

Brief Summary

On 11th of March 2020, WHO characterized COVID-19 infection as a Pandemic. After the COVID-19 infection is declared as a Pandemic there was an outburst regarding COVID-19 Research. The Research interest led to registration of Interventional and Observational studies world wide. There are constant efforts by Health care workers to seek information regarding the Interventional and Observational studies which can help in decision making regarding effective handling of COVID-19 infected patients. It is also important to track on the happenings in various frontiers of COVID-19 Research in view of historical interest and clinical relevance. This Observational Cross sectional study aims to explore the completed Researches in WHO-compliant registries to understand the trends of COVID-19 Research. This study aims to get a birds eye view of ongoing COVID-19 Research scenario worldwide. This study results can directly benefit the worldwide Academicians and Health Care Professionals to understand the ongoing COVID-19 Research trends.

Conditions

COVID-19

Keywords

Research trends, COVID-19, Pandemic, Interventional studies, Observational studies

Outcome Measures

Primary Outcomes (3)

• Geographical distribution of the interventional studies after 11th of March 2020.

  To understand the geographical distribution of the interventional studies after 11th of March 2020.

  15th of August 2020

• Geographical distribution of the Observational studies after 11th of March 2020.

  To understand the geographical distribution of the Observational studies after 11th of March 2020.

  15th of August 2020

• Monthly Research study completion rate as per geographic distribution of the Research.

  To understand the monthly Research study completion rate as per geographic distribution of the Research.

  15th of August 2020

Secondary Outcomes (5)

• Statistical correlation of the interventional studies Research with developed, developing and under developed countries.

  15th of August 2020

• Statistical correlation of the observational studies Research with developed, developing and under developed countries.

  15th of August 2020

• Statistical correlation of the Drug based interventional studies Research with developed, developing and under developed countries.

  15th of August 2020

• Statistical correlation of the Diagnostic test based interventional studies Research with developed, developing and under developed countries.

  15th of August 2020

• Statistical correlation of the Device based interventional studies Research with developed, developing and under developed countries.

  15th of August 2020

Study Arms (2)

Completed Interventional studies

Interventional studies in the WHO-compliant registries database which are registered and completed before 11th March 2020.

Drug: Convalescent Plasma Transfusion; Drug: Hydroxychloroquine; Drug: DAS181; Drug: Ivermectin; Drug: Interferon Beta-1A

Completed Observational studies

Observational studies in the WHO-compliant registries database which are registered and completed before 11th March 2020.

Drug: Convalescent Plasma Transfusion; Drug: Hydroxychloroquine; Drug: DAS181; Drug: Ivermectin; Drug: Interferon Beta-1A

Interventions

Convalescent Plasma Transfusion DRUG

Convalescent Plasma Transfusion to COVID-19 infected patients.

Completed Interventional studies; Completed Observational studies

Hydroxychloroquine DRUG

Hydroxychloroquine administration to COVID-19 infected patients.

Completed Interventional studies; Completed Observational studies

DAS181 DRUG

DAS181 administration to COVID-19 infected patients.

Completed Interventional studies; Completed Observational studies

Ivermectin DRUG

Ivermectin administration to COVID-19 infected patients.

Completed Interventional studies; Completed Observational studies

Interferon Beta-1A DRUG

Interferon Beta-1A administration to COVID-19 infected patients.

Completed Interventional studies; Completed Observational studies

Eligibility Criteria

• Age: 1 Year+
• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Subjects who are infected with COVID-19. Healthy Volunteers who respond to survey. Subjects who have recently recovered from COVID-19 infection.

You may qualify if:

• Interventional studies in the WHO-compliant registries database which are registered and completed after 11th of March 2020 until 15th of August 2020.
• Observational studies in the WHO-compliant registries database which are registered and completed after 11th of March 2020 until 15th of August 2020.

You may not qualify if:

• Interventional studies in the WHO-compliant registries database which are registered and completed before 11th March 2020.
• Observational studies in the WHO-compliant registries database which are registered and completed before 11th March 2020.

Sponsors & Collaborators

• Qassim University: lead

MeSH Terms

Conditions

COVID-19

Interventions

Hydroxychloroquine; oplunofusp; Ivermectin; Interferon beta-1a

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Chloroquine; Aminoquinolines; Quinolines; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, Fused-Ring; Heterocyclic Compounds; Macrolides; Polyketides; Lactones; Organic Chemicals; Interferon-beta; Interferon Type I; Interferons; Cytokines; Intercellular Signaling Peptides and Proteins; Peptides; Amino Acids, Peptides, and Proteins; Proteins; Biological Factors

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: July 3, 2020
• First Posted: July 7, 2020
• Study Start: July 25, 2020
• Primary Completion: August 15, 2020
• Study Completion: September 20, 2020
• Last Updated: July 7, 2020

Record last verified: 2020-07

Data Sharing

• IPD Sharing: Will not share