Effect of Lumbar Stabilization on Knee OA

NCT04458753 | Completed

• 1 other identifier: 012/002731
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This study will be conducted to investigate the role of lumbar core strengthening in reducing knee pain and disability, and improving knee proprioception and Quadriceps strength in patients with knee OA.

Conditions

Knee Osteoarthritis

Keywords

Knee osteoarthritis; Lumbar core strengthening exercises; Dpinal stabilization training

Outcome Measures

Primary Outcomes (2)

• Average Knee Pain during last week

  Measured with visual analogue scale; 10 cm line, zero: no pain, 10: worst pain, during last week

  1year

• Quadriceps isometric strength

  Measured with Hand held dynamometer from supine, knee flexed 30 degrees

  1 year

Secondary Outcomes (2)

• Disability

  1 year

• Knee Proprioception absolute angular error

  1year

Study Arms (2)

Lumbar focused + knee focused exercise group

EXPERIMENTAL

Will receive strengthening of back , abdominal, and quadriceps muscles, and stretching if calf and Hamstring muscles

Other: Lumbar focused exercises; Other: Knee focused exercises

Knee focused exercise group

ACTIVE COMPARATOR

Will receive strengthening of quadriceps and stretching of calf and Hamstring muscles

Other: Knee focused exercises

Interventions

Lumbar focused exercises OTHER

Transersus abdominis activation Multifidus activation Back extension exercise Curl up abdominal exercise

Also known as: Core training, Core stability

Lumbar focused + knee focused exercise group

Knee focused exercises OTHER

Strengthening of quadriceps Stretching of calf and Hamstring muscles

Also known as: Traditional knee program

Knee focused exercise group; Lumbar focused + knee focused exercise group

Eligibility Criteria

• Age: 40 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Knee pain for most days of previous month
• Age 40- 65 years Knee OA grade 2-3 on kellgren- Lawrence grading scale. Unilateral or bilateral (provided that they radiologically have one knee ≤ grade 1 on KL score, and clinically pain ≤2 in VAS. The more severally affected knee will be included in evaluation and treatment) BMI= 25-32 kg/m2.

You may not qualify if:

• Symptomatic hip OA Hip or pelvis trauma Knee or hip infection Congenital or developmental disorder of lower limbs Intra-articular corticosteroid or hyaluronic acid injection into the knee within the last 3 months.
• Previous surgery of the affected knee or spine. Significant injury to the knee within the past 6 months. Any disease or medication worsens physical function or hampers with knee evaluation (e.g. rheumatoid arthritis, canal stenosis..).

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Kasr AlAiny hospital, Cairo university

Giza, Egypt

Location

Related Publications (1)

• Foroughi F, Sobhani S, Yoosefinejad AK, Motealleh A. Added Value of Isolated Core Postural Control Training on Knee Pain and Function in Women With Patellofemoral Pain Syndrome: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2019 Feb;100(2):220-229. doi: 10.1016/j.apmr.2018.08.180. Epub 2018 Sep 26.

  PMID: 30267667 RESULT

MeSH Terms

Conditions

Osteoarthritis, Knee

Interventions

Core Stability

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Postural Balance; Proprioception; Vestibulocochlear Physiological Phenomena; Physiological Phenomena; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Sensation; Nervous System Physiological Phenomena

Study Officials

• Mohammed S Abdelsalam, Ass prof

  Cairo University

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Patients will not know in which group they assigned
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Model Details: Two groups; group A will be treated with exercises directed to lumbar and knee, group B will receive exercises directed to knee only. 3 sessions/ week for 4 weeks

Study Record Dates

• First Submitted: July 1, 2020
• First Posted: July 7, 2020
• Study Start: June 10, 2020
• Primary Completion: October 30, 2021
• Study Completion: November 30, 2021
• Last Updated: March 9, 2022

Record last verified: 2022-03

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)