NCT04455451

Brief Summary

Multi-center retrospective and prospective observational study of Covid-19 patients with severe or critical illness treated on a German ICU

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,054

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2020

Geographic Reach
1 country

27 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 1, 2020

Completed
1 day until next milestone

First Posted

Study publicly available on registry

July 2, 2020

Completed
1 month until next milestone

Study Start

First participant enrolled

August 6, 2020

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 15, 2021

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2021

Completed
Last Updated

January 12, 2022

Status Verified

September 1, 2021

Enrollment Period

1 year

First QC Date

July 1, 2020

Last Update Submit

January 11, 2022

Conditions

COVIDARDS

Outcome Measures

Primary Outcomes (1)

  • Mortality

    ICU Mortality of patients

    up to 150 days

Secondary Outcomes (1)

  • ICU length of stay

    up to 150 days

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adults admitted for ICU therapy due to severe or critical Covid-19

You may qualify if:

  • Age above 18 years
  • Covid-19 disease (positive SARS-CoV-2 PCR)

You may not qualify if:

  • none

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (27)

RWTH Aachen - Department for operative Intensive Care Medicine and intermediate Care

Aachen, Germany

Location

Zollernalbklinikum

Balingen, Germany

Location

Charité Universitätsmedizin Berlin

Berlin, Germany

Location

UH Bochum - Department for Anesthesiology and Intensive Care Medicine

Bochum, Germany

Location

Universitätsklinikum Bonn

Bonn, Germany

Location

Klinikum der Universität Witten/Herdecke - Köln / Klinik für Anästhesiologie und operative Intensivmedizin

Cologne, Germany

Location

Universitätsklinikum Carl Gustav Carus Dresden

Dresden, Germany

Location

Ev. Krankenhaus Bethesda Duisburg Klinik für Anästhesiologie und Intensivmedizin

Duisburg, Germany

Location

Univerrsitätsklinikum Düsseldorf

Düsseldorf, Germany

Location

Universitätsklinikum Essen

Essen, Germany

Location

Universitätsklinikum Frankfurt

Frankfurt, Germany

Location

University Hospital Freiburg - Department for Anesthesiology and Intensive Care Medicine

Freiburg im Breisgau, Germany

Location

Universitätsklinikum Giessen Klinik für Anaesthesiologie und operative Intensivmedizin

Giessen, Germany

Location

Universitätsmedizin Göttingen Klinik für Anästhesiologie

Göttingen, Germany

Location

Universitätsklinikum Greifswald

Greifswald, Germany

Location

Universitätsklinikum Halle

Halle, Germany

Location

University Hospital Heidelberg - Department for Anesthesiologie and Intensive Care Medicine

Heidelberg, Germany

Location

Universitätsklinikum des Saarlandes

Homburg/Saar, Germany

Location

Universitätsklinikum Leipzig

Leipzig, Germany

Location

UKSH Campus Lübeck - Department for Anesthesiology and Intensive Care Medicine

Lübeck, Germany

Location

University Hospital Magdeburg - Department for Anesthesiology and Intensive Care Medicine

Magdeburg, Germany

Location

Universitätsklinikum Marburg

Marburg, Germany

Location

Technische Universität München

München, Germany

Location

Oberschwabenklinik Ravensburg Klinik für Anästhesie-, Intensiv-, Notfall- und Schmerzmedizin

Ravensburg, Germany

Location

University Hospital Tübingen - Department for Anesthesiology and Intensive Care Medicine

Tübingen, Germany

Location

Universitätsklinikum Ulm

Ulm, Germany

Location

Universitätsklinikum Würzburg Klinik und Poliklinik für Anästhesiologie, Intensivmedizin und Schmerztherapie

Würzburg, Germany

Location

Related Publications (1)

  • Magunia H, Lederer S, Verbuecheln R, Gilot BJ, Koeppen M, Haeberle HA, Mirakaj V, Hofmann P, Marx G, Bickenbach J, Nohe B, Lay M, Spies C, Edel A, Schiefenhovel F, Rahmel T, Putensen C, Sellmann T, Koch T, Brandenburger T, Kindgen-Milles D, Brenner T, Berger M, Zacharowski K, Adam E, Posch M, Moerer O, Scheer CS, Sedding D, Weigand MA, Fichtner F, Nau C, Pratsch F, Wiesmann T, Koch C, Schneider G, Lahmer T, Straub A, Meiser A, Weiss M, Jungwirth B, Wappler F, Meybohm P, Herrmann J, Malek N, Kohlbacher O, Biergans S, Rosenberger P. Machine learning identifies ICU outcome predictors in a multicenter COVID-19 cohort. Crit Care. 2021 Aug 17;25(1):295. doi: 10.1186/s13054-021-03720-4.

    PMID: 34404458DERIVED

Related Links

Study Officials

  • Peter Rosenberger, MD, PhD

    University Hospital Tübingen

    PRINCIPAL INVESTIGATOR

  • Harry Magunia, MD

    University Hospital Tübingen

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 1, 2020

First Posted

July 2, 2020

Study Start

August 6, 2020

Primary Completion

August 15, 2021

Study Completion

September 30, 2021

Last Updated

January 12, 2022

Record last verified: 2021-09

Data Sharing

IPD Sharing
Will not share

Locations

DE(27)