NCT04455386

Brief Summary

Comparative Study on Accuracy of Different Diagnostic Methods of Lateral Collateral Ligament Injury of Ankle

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
75

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Nov 2019

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2019

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

June 27, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 2, 2020

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
Last Updated

April 10, 2023

Status Verified

April 1, 2023

Enrollment Period

4.2 years

First QC Date

June 27, 2020

Last Update Submit

April 6, 2023

Conditions

Keywords

Lateral Ligament complexAnkleDiagnostic MethodsChronic Lateral Instability of Ankle

Outcome Measures

Primary Outcomes (4)

  • anterior talar translation and talar tilt

    Assess the instability through stress X ray of the ankle

    before operation

  • length of ATFL and CFL in relax and stress position

    Assess the instability through Ultrasound of the ankle

    before operation

  • Morphology of ATFL and CFL

    Assess the ATFL and CFL through MRI of the ankle

    before operation

  • status of ATFL and CFL

    evaluation of ATFL and CFL during operation

    during operation

Secondary Outcomes (2)

  • avulsion fracture

    before operation

  • osteophyte

    before operation

Study Arms (3)

stable

The anterior drawer test and/or talar tilt test are negative and the ankle joint is stable.

Diagnostic Test: Stress radiography,Anterior drawer test,Stress ultrasound,Computed tomography, Magnetic resonance imaging,Arthroscopy

slightly instable

The anterior drawer test and/or talar tilt test are slightly positive and the ankle joint is partially instable.

Diagnostic Test: Stress radiography,Anterior drawer test,Stress ultrasound,Computed tomography, Magnetic resonance imaging,Arthroscopy

obviously instable

The anterior drawer test and/or talar tilt test is significantly positive, with significantly instable. The ankle joint is completely instable and can featured with dimple sign.

Diagnostic Test: Stress radiography,Anterior drawer test,Stress ultrasound,Computed tomography, Magnetic resonance imaging,Arthroscopy

Interventions

All patients suspected chronic ankle instability, will perform an anterior drawer test, stress ultrasound, computed tomography, magnetic resonance imaging of ankle. Patients with chronic ankle instability will be recommended to perform an arthroscopic repair if non-operative treatment failed.

obviously instableslightly instablestable

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with chronic lateral ligament complex injury of the ankle were divided into 3 groups and each group with 25 cases, according to the anterior drawer test and talar tilt test.

You may qualify if:

  • Chronic lateral ankle ligament injury due to ankle sprain in patients over 16 years of age.

You may not qualify if:

  • Acute and subacute injury of the lateral ligament complex of the ankle joint (less than 3 months), malalignment of ankle (more than 5 degrees), osteoarthritis (stage IV).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Institute of Sports Medicine

Beijing, Beijing Municipality, 100000, China

RECRUITING

Study Officials

  • Qinwei Guo

    Peking University Third Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
associated professor

Study Record Dates

First Submitted

June 27, 2020

First Posted

July 2, 2020

Study Start

November 1, 2019

Primary Completion

December 31, 2023

Study Completion

December 31, 2023

Last Updated

April 10, 2023

Record last verified: 2023-04

Data Sharing

IPD Sharing
Will not share

Locations