NCT04450420

Brief Summary

TCC-PASTE is a randomised controlled trial comparing a simulation based training curriculum with standard training for ophthalmology residents learning to perform tunnel construction in manual small incision cataract surgery. After obtaining informed consent, participating trainees will be randomly assigned to learn to perform tunnel construction either through the simulation based curriculum or through the standard curriculum at their institute. Trainees assigned to simulation will learn through studying an eBook, participating in training sessions supported by repeated practice on a virtual reality simulator, and supervised training in live surgery to facilitate transfer of skill acquired in simulation to the operating room. To determine the effect of simulation based training, we will assess the number of errors trainees perform in the initial part of their intraoperative learning curve.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for phase_2

Timeline
Completed

Started Aug 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 28, 2018

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 16, 2019

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2020

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

June 19, 2020

Completed
10 days until next milestone

First Posted

Study publicly available on registry

June 29, 2020

Completed
Last Updated

June 29, 2020

Status Verified

June 1, 2020

Enrollment Period

12 months

First QC Date

June 19, 2020

Last Update Submit

June 24, 2020

Conditions

Keywords

cataractMSICSmanual small incision cataract surgerysurgical simulationsimulation

Outcome Measures

Primary Outcomes (1)

  • Total surgical errors

    Incidence of pre-specified errors during tunnel construction through video-based assessment: uveal prolapse (UP), buttonhole incision (BI), premature entry (PE), Descemet's detachment (DD), laceration of upper wall (UL), laceration of lateral walls of tunnel (LL), corneal endothelial touch (ET), contact with iris, (IC) and contact with the lens (LC).

    12 weeks

Secondary Outcomes (17)

  • Major surgical errors

    12 weeks

  • Minor surgical errors

    12 weeks

  • Surgical product/outcome assessment: scleral groove

    12 weeks

  • Surgical product/outcome assessment: tunnel dissection

    12 weeks

  • Surgical product/outcome assessment: paracentesis

    12 weeks

  • +12 more secondary outcomes

Other Outcomes (5)

  • Incidence of any surgical error or self-reported intervention by supervising surgeon to prevent error

    12 weeks

  • Incidence of major surgical error or self-reported intervention by supervising surgeon to prevent error

    12 weeks

  • Incidence of minor surgical error or self-reported intervention by supervising surgeon to prevent error

    12 weeks

  • +2 more other outcomes

Study Arms (2)

Simulation based curriculum

EXPERIMENTAL

Three phases: 1. Self-study of an eBook - Participating trainees will be required to learn material pertaining to tunnel construction and general surgical principles during SICS from an eBook that has been developed by HelpMeSee. 2. Instructor led teaching - didactic training, lab activities to gain familiarity with instruments, simulator based training through deliberate practice, and debriefing with instructor. 3. Instructor supervised performance of surgery on patients in the operating room.

Other: Simulation based curriculum

Standard training

ACTIVE COMPARATOR

Current standard curriculum for resident training.

Other: Standard training

Interventions

See arm/group description

Simulation based curriculum

See arm/group description

Standard training

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Enrolled in a training program at a partner institute;
  • No or minimal prior experience with MSICS (trainees within the first 2-3 months of matriculation, or having performed fewer than 20 procedures as the main surgeon but no more than 5 MSICS procedures within 6 months preceding participation in TCC-PASTE);
  • Provide informed consent to participate in the study;
  • Able to participate in routine patient care activities, as required by the partner institute, without the need to take overnight call for the duration corresponding to the simulation training phase.

You may not qualify if:

  • Performed scleral tunnel construction as the main surgeon in 20 or more procedures;
  • Prior experience with the HelpMeSee simulator or participation in the HelpMeSee simulation training curriculum.
  • Required to take overnight call for the duration corresponding to simulation training phase.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

HelpMeSee Inc.

New York, New York, 10018, United States

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Expert raters assessing outcomes by watching videos of surgery were masked to the identity of the participating surgeon, their institutional affiliation, and the sequence in which they performed procedures in the trial.
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 19, 2020

First Posted

June 29, 2020

Study Start

August 28, 2018

Primary Completion

August 16, 2019

Study Completion

June 1, 2020

Last Updated

June 29, 2020

Record last verified: 2020-06

Data Sharing

IPD Sharing
Will not share

Locations