Effect of Neurodynamics Nerve Flossing on Femoral Neuropathy in Haemophilic Patients

NCT04448275 | Completed DMC

• 1 other identifier: P.T./REC /012/002733
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

To investigate the effect of Neurodynamics Nerve flossing on femoral neuropathy in patients with haemophilia Background: heamophilia is one of the serious chronic disorders in children and adolescents which results in less physical activities and restlessness hours than their peer. HYPOTHESES: This study will hypnotize that: Neurodynamics Nerve flossing will have a significant effect on femoral neuropathy in patients with haemophilia RESEARCH QUESTION: will the Neurodynamics Nerve flossing has an effect on femoral neuropathy in patients with haemophilia?

Conditions

Femoral Neuropathy in Haemophilic Patients

Keywords

Neurodynamics,; Nerve flossing;; femoral neuropathy; , haemophilia,

Outcome Measures

Primary Outcomes (3)

• Electromyography Nerve conduction study

  Femoral Nerve motor conduction velocity (m/sec.) , via the Neuropack S1 MEB9004 EMG device

  12 weeks

• Femoral Nerve Tension Test, for femoral nerve injury

  Femoral Nerve Tension Test is a neural tension test used to stress the femoral nerve A positive test was be reproduction of the patient's symptoms as burning discomfort in the groin or anterior thigh occurred if there was femoral nerve involvement.

  12 weeks

• Manual muscle test, Oxford five grades of muscle power assessment

  The group Manual muscle test was used for testing the strength of iliopsoas and quadriceps muscles, according to the Oxford Scale as the Muscle strength is often rated on a scale of 0/5 as follow: (0/5) no contraction of muscle, (1/5) muscle flicker contraction, but no movement (2/5) movement possible, but not against gravity (test the joint in its horizontal plane), (3/5) movement possible against gravity, but not against resistance by the therapist, (4/5) movement possible against some resistance by the examiner and (5/5) normal strength

  12 weeks

Study Arms (2)

study group

EXPERIMENTAL

received conventional selected exercise program and in addition to Neurodynamics Nerve flossing for femoral nerve

Other: Neurodynamics Nerve flossing; Other: conventional selected exercise program

control group

EXPERIMENTAL

received conventional selected exercise program in form of: Ultrasound therapy The flexibility exercises for iliopsoas \& quadriceps in heamophilic patient The iliopsoas \& quadriceps muscles strength exercise

Other: conventional selected exercise program

Interventions

Neurodynamics Nerve flossing OTHER

Neurodynamics Nerve flossing for femoral nerve that includes two techniques inform of: "slider technique" and the second is the "tensioner technique

study group

conventional selected exercise program OTHER

Ultrasound therapy The flexibility exercises for iliopsoas \& quadriceps The iliopsoas \& quadriceps muscles strength exercise

control group; study group

Eligibility Criteria

• Age: 12 Years - 16 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• hemophilia A or B, all the patients
• positive femoral nerve tension test
• the Manual muscle test for iliopsoas and quadriceps muscles in all patients not less than grade 2 according to the oxford scale
• the age ranging from (12:16) years
• all the participants will be able to communicate verbally ,obey commands and instructions and co-operate with testing and training protocols

You may not qualify if:

• any participants have auditory, visual and sever cardiac disorders
• Patients who have mild degree of hemophilia
• Patients who have joint, muscle bleeding or pain in the lower limb in the preceding 3 weeks
• patients with any other neurological disorders or musculoskeletal disorders or deformities of the lower limb.

Sponsors & Collaborators

• Lama Saad El-Din Mahmoud: lead

Study Sites (1)

October 6 University

Giza, El-Sheikh Zayed City Giza 1133 Egypt, Egypt

Location

MeSH Terms

Conditions

Femoral Neuropathy; Hemophilia A

Condition Hierarchy (Ancestors)

Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Blood Coagulation Disorders, Inherited; Blood Coagulation Disorders; Hematologic Diseases; Hemic and Lymphatic Diseases; Coagulation Protein Disorders; Hemorrhagic Disorders; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

• Lama S Mahmoud, PHD

  lecturer , department of Neuromuscular Disorders and its surgery, faculty of physical therapy O6U physical therapy

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Lecturer of physical therapy, Department of Neuromuscular disorders and its surgery, faculty of physical therapy, october 6 univerisity

Model Details: control group which received conventional selected exercise program in form of Ultrasound therapy The flexibility exercises for iliopsoas \& quadriceps The iliopsoas \& quadriceps muscles strength exercise and study group received the same exercise training program in addition to Neurodynamics Nerve flossing three times per week for three successive months

Study Record Dates

• First Submitted: June 22, 2020
• First Posted: June 25, 2020
• Study Start: June 30, 2020
• Primary Completion: September 30, 2020
• Study Completion: October 30, 2020
• Last Updated: January 6, 2021

Record last verified: 2021-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)