NCT04446923

Brief Summary

The present study evaluates the effects of to compare bactericidal efficacy using the reference antiseptic product propan-ol-1 60% using the hand rub method versus hand scrub method in order to test if pass the standard european norm 12791.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for phase_4

Timeline
Completed

Started Jun 2020

Shorter than P25 for phase_4

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 22, 2020

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 25, 2020

Completed
3 days until next milestone

Study Start

First participant enrolled

June 28, 2020

Completed
20 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 18, 2020

Completed
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 20, 2020

Completed
Last Updated

July 21, 2020

Status Verified

July 1, 2020

Enrollment Period

20 days

First QC Date

June 22, 2020

Last Update Submit

July 20, 2020

Conditions

Keywords

hand antisepsis

Outcome Measures

Primary Outcomes (1)

  • Reduction of bacterial load immediately after hand scrub

    Participants will scrub the liquid vigorously from hand to the wrists according with the standard handrub procedure.

    Change from bacterial load at 5 minutes.

Secondary Outcomes (1)

  • Reduction of bacterial load after 3 hours of hand scrub

    Change from bacterial load at 3 hours.

Study Arms (2)

Hand antisepsis by scrub

EXPERIMENTAL

Hand antisepsis by scrub using propan-ol-1 60%

Drug: Hand antisepsis by scrub

Hand antisepsis by rub

ACTIVE COMPARATOR

Hand antisepsis by rub using propan-ol-1 60%

Drug: Hand antisepsis by scrub

Interventions

Surgical Hand scrubbing using P-1 of both hands using a sterile disposable surgical scrub brush with plastic bristles on one side and a foam sponge on the other side.

Also known as: Propanolol
Hand antisepsis by scrub

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Participants without systemic pathologies, with healthy skin of the hands and short fingernails.
  • They do not use substances with antibacterial action.

You may not qualify if:

  • Taken antibiotics before 10 days of the intervention.
  • Wear any jewellery on the hands.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ricardo Becerro de Bengoa Vallejo

Madrid, 28040, Spain

Location

MeSH Terms

Conditions

Skin DiseasesSurgical Wound Infection

Interventions

Propranolol

Condition Hierarchy (Ancestors)

Skin and Connective Tissue DiseasesWound InfectionInfectionsPostoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

PhenoxypropanolaminesPropanolaminesAmino AlcoholsAlcoholsOrganic ChemicalsPropanolsAminesNaphthalenesPolycyclic Aromatic HydrocarbonsHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbonsPolycyclic Compounds

Study Officials

  • Ricardo Becerro de Bengoa Vallejo, PhD

    Ricardo becerro de Bengoa Vallejo

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
The samples will be sent to the laboratory with numbers.
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: Crossover design is used
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

June 22, 2020

First Posted

June 25, 2020

Study Start

June 28, 2020

Primary Completion

July 18, 2020

Study Completion

July 20, 2020

Last Updated

July 21, 2020

Record last verified: 2020-07

Data Sharing

IPD Sharing
Will not share

A number will be assigned to each participant

Locations