NCT04441593

Brief Summary

This pilot study seeks to provide effect size estimates and test feasibility of a novel, integrated behavioral approach to reduce heavy drinking and chronic pain among patients in HIV-care delivered via internet-based videoconferencing.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
49

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2020

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 18, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 22, 2020

Completed
6 months until next milestone

Study Start

First participant enrolled

December 23, 2020

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 2, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 2, 2024

Completed
Last Updated

March 13, 2024

Status Verified

March 1, 2024

Enrollment Period

3.1 years

First QC Date

June 18, 2020

Last Update Submit

March 11, 2024

Conditions

Outcome Measures

Primary Outcomes (4)

  • Alcohol Time Line Follow-Back (30)- Heavy Drinking Episodes

    Number of heavy drinking episodes NIAAA criteria (5+drinks men/ 4+ drinks women)

    Past 30 days

  • Alcohol Time Line Follow-Back (30) - Average Drinks per Week

    Average number of standard alcohol-containing drinks in the past 30 days

    Past 30 days

  • Brief Pain Inventory - Pain Severity

    BPI is an 11-point scale anchored with "0" best and "10" is worst Scale range 0-10

    Past 7 days

  • Brief Pain Inventory - Pain Interference

    BPI is an 11-point scale anchored with "0" best and "10" is worst Scale range 0-10. Pain Interference is measured as the mean of 7-items each rated on an 11-point scale

    Past 7-Days

Secondary Outcomes (3)

  • Short Inventory of Alcohol Problems-Revised

    3 months

  • Goal Systems Assessment Battery-Alcohol

    Past 30 days

  • Goal Systems Assessment Battery-Pain

    Past 30 days

Study Arms (2)

Intervention

EXPERIMENTAL

Videoconferencing Intervention for Heavy Drinking and Chronic Pain

Behavioral: Motivational and Cognitive-Behavioral Management for Alcohol and Pain (MCBMAP)

Control

ACTIVE COMPARATOR

Treatment as Usual

Behavioral: Treatment as Usual

Interventions

Videoconferencing intervention to reduce alcohol use and chronic pain interference and severity

Also known as: Intervention
Intervention

Psychoeducation and Information about Treatment Resources

Also known as: Control
Control

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • engaged in HIV care, heavy drinking defined as more than 7/14 drinks per week for women/men or by a single episode of 4/5 (women/men), chronic (at least 3 months duration) moderate or greater (4 or more on the severity scale of the BPI, and non-cancer related pain

You may not qualify if:

  • psychoactive medication for pain or alcohol use for fewer than 2 months
  • history of bipolar disorder or schizophrenia
  • current expressed suicidal intent
  • prior history of alcohol withdrawal related seizures or delirium tremens
  • current behavioral treatment for pain or alcohol use
  • any scheduled surgery within the next 6 months or acute life threatening illness that requires treatment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Boston University Department of Psychological and Brain Sciences

Boston, Massachusetts, 02215, United States

Location

General Clinical Research Unit, Boston University

Boston, Massachusetts, 02215, United States

Location

MeSH Terms

Conditions

Alcohol Drinking

Interventions

EthanolMethodsTherapeutics

Condition Hierarchy (Ancestors)

Drinking BehaviorBehavior

Intervention Hierarchy (Ancestors)

AlcoholsOrganic ChemicalsInvestigative Techniques

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Three and six month assessments will be conducted by RA who is masked to intervention condition
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Compare Intervention to Control Condition in a Between Subjects Design
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 18, 2020

First Posted

June 22, 2020

Study Start

December 23, 2020

Primary Completion

February 2, 2024

Study Completion

February 2, 2024

Last Updated

March 13, 2024

Record last verified: 2024-03

Data Sharing

IPD Sharing
Will share

For proposals that contain analyses that are not already planned or in progress, the investigators will make data available for collaboration with a study investigator, provided IRB and other appropriate regulatory approvals are obtained (including but not limited to Federal and Boston University IRB review and approval). Data to be shared will be de-identified to minimize the risk of deductive disclosure. Documentation will be provided for all shared data including copies of data collection forms, schedule of study assessments, data dictionaries documenting all original and derived variables, descriptive statistics for all variables included in the data sets, and a written description of the study conduct and noteworthy details anticipated to potentially affect data interpretation. Costs associated with producing data sets and analysis will be the responsibility of investigators seeking the data.

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
Twelve months following request, de-identified data will be available to investigators upon request. This access will be provided for 7 years following publication of main trial
Access Criteria
Specific data may be shared based on proposals received and reviewed by the study investigators and determined to have scientific merit. Limited public-use data sets may also be prepared and made available in a web-data archive to be developed and maintained by the data coordinating center (BEDAC).

Locations