Evaluation of Implementation and Effectiveness of Computerised Brain Training for Older Adults

NCT04439591 | Completed

• 1 other identifier: 2017/00611
• Study Type: interventional
• Target: 94
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the implementation and effectiveness of a group-based brain-computer interface cognitive training among community dwelling older adults in Singapore. A 12-week bi-weekly programme was conducted in community centres. During these sessions, participants played games targeting cognitive domains such as attention, memory, and decision making, using a mobile application (Memorie). Selected games were paired with an electroencephalography headset (Senzeband) which quantified participants' attention level into scores that affected the participants' in-game avatar control or game performance. Each participant paid a subsidized fee of SGD$20 for the programme.

Conditions

Cognition

Keywords

Computerised cognitive training; Healthy older adults

Outcome Measures

Primary Outcomes (2)

• Change in cognition from baseline at 12 weeks

  Repeated Battery for the Assessment of Neuropsychological Status (RBANS). The maximum score that an individual can get is 160, and higher scores indicate better performance. The tests consists of 12 subtests grouped into 5 domains of cognition.

  Baseline and 12 weeks

• Change in attention from baseline at 12 weeks

  Colour Trails Test. Time taken to complete the actual trial was recorded, along with the number of near-misses, prompts, number sequence errors, and color sequence errors.

  Baseline and 12 weeks

Secondary Outcomes (2)

• Change in balance from baseline at 12 weeks

  Baseline and 12 weeks

• Change in walking gait from baseline at 12 weeks

  Baseline and 12 weeks

Study Arms (2)

Intervention group

EXPERIMENTAL

Intervention group undergoes computerised brain training programme first.

Other: Computerised cognitive training

Control group

OTHER

Waitlist control group: control group undergoes programme after intervention group has completed it in a crossover design.

Other: Computerised cognitive training

Interventions

Computerised cognitive training OTHER

A 12-week bi-weekly group-based computerised cognitive training programme conducted in community centres

Control group; Intervention group

Eligibility Criteria

• Age: 55 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Above or equal to 55 years old
• Sedentary lifestyle (exercise less than or equal to once week)
• Literate in English/Chinese
• Able to travel to study site independently

You may not qualify if:

• Had significant cognitive impairment (Mini Mental State Examination score \<=23) or presence of known neuropsychiatric disorders
• Geriatric Depression Scale \>9
• Presence of a severe walking or balance impairments
• Previously completed a cognitive training program within the last year
• Color-blindness
• Plans to begin a balance program during the study period
• Self-reported presence of vertigo
• Visual acuity of less than 20/80
• Currently using psychotropic medications

Sponsors & Collaborators

• Geriatric Education and Research Institute: lead
• Neeuro Pte Ltd: collaborator

Study Sites (1)

Geriatric Education and Research Institute

Singapore, 768024, Singapore

Location

Related Publications (21)

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• Yeo PS, Nguyen TN, Ng MPE, Choo RWM, Yap PLK, Ng TP, Wee SL. Evaluation of the Implementation and Effectiveness of Community-Based Brain-Computer Interface Cognitive Group Training in Healthy Community-Dwelling Older Adults: Randomized Controlled Implementation Trial. JMIR Form Res. 2021 Apr 27;5(4):e25462. doi: 10.2196/25462.

  PMID: 33904819 DERIVED

Study Officials

• Shiou Liang Wee, PhD

  Geriatric Education and Research Institute

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 17, 2020
• First Posted: June 19, 2020
• Study Start: August 1, 2017
• Primary Completion: November 9, 2018
• Study Completion: November 9, 2018
• Last Updated: June 22, 2020

Record last verified: 2020-06

Data Sharing

• IPD Sharing: Will not share

Locations

SG (1)