COVID-19 Critically Ill Patients' Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units

NCT04433325 | Unknown

• 1 other identifier: 35RC20_3091_TOCCIP
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 2

Brief Summary

Since early 2020, France knows a sanitary crisis with a massive influx of COVID-19 patients admitted in Intensive Care Units (ICU). It led to a saturation of the French health system, especially in some geographic areas such as East of France or Paris region. Therefore, authorities decided to transfer some critically ill patients from these crowded ICUs to less busy regional ICUs. it was done for the first time by medical train transportation. Knowing that the investigators lack experience regarding this type of medical evacuation, regarding the high number of transferred patients, with such a logistic effort, the investigators decided to study this phase of the COVID-19 sanitary crisis in order to draw a feedback. So far, there are no data in the literature regarding this topic.

Conditions

COVID-19; Intensive Care Unit Syndrome

Keywords

Medical transport by train

Outcome Measures

Primary Outcomes (1)

• number of death

  to evaluate mortality

  at Intensive Care Units discharge, an average of 1 months

Secondary Outcomes (7)

• number of infections

  from date of admission until Intensive Care Units discharge, assessed up to 1 months

• number of days of mechanical ventilation

  from date of admission until Intensive Care Units discharge, assessed up to 1 months

• number of days of sedation

  from date of admission until Intensive Care Units discharge, assessed up to 1 months

• number of days of use of neuromuscular blocking agents

  from date of admission until Intensive Care Units discharge, assessed up to 1 months

• number of days of vasopressor use

  from date of admission until Intensive Care Units discharge, assessed up to 1 months

Study Arms (2)

Patients transferred

Patients transferred from Paris's Intensive Care Units

Patients not transferred

Patients admitted in Intensive Care Units with no transfer from Paris

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

COVID-19 positive patients admitted in Intensive Care Unit between 15/03/2020 and 15/04/2020

You may qualify if:

• Age \> 18 years
• COVID-19 positive patients admitted in Intensive Care Unit between 15/03/2020 and 15/04/2020
• Regarding case group : Patients transferred from Paris's ICU
• Regarding case control group : Patients admitted in ICU with no transfer from Paris

You may not qualify if:

• \- \> 18 years under legal protection and patients with liberty restriction

Sponsors & Collaborators

• Rennes University Hospital: lead

Study Sites (2)

CHU Poitiers

Poitiers, France

Location

CHU Tours

Tours, France

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Benoît Painvin

  CHU Rennes

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Nicolas Mevel

CONTACT

0299282555; dri@chu-rennes.fr

Anne Ganivet

CONTACT

0299282555; anne.ganivet@chu-rennes.fr

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 12, 2020
• First Posted: June 16, 2020
• Study Start: June 1, 2020
• Primary Completion: July 1, 2020
• Study Completion: September 1, 2020
• Last Updated: June 16, 2020

Record last verified: 2020-06

Locations

FR (2)