Magnetic Resonance Imaging to Detect Signs of Viral Pneumonia in Patients With Coronavirus Infection.

NCT04424355 | Completed

• 1 other identifier: 2020-2
• Study Type: observational
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

Since the onset of the COVID-19 pandemic, the importance of chest computed tomography (CT) in detecting signs of viral pneumonia has become clear from the literature. However, the increased patient flow creates an additional pressure on CT centers. We believe, the use of chest magnetic resonance imaging (MRI) can help to test patients for CОVID-19 when CT scan is not available. Lung MRI may be useful in routing a patient in a difficult epidemiological situation.

Conditions

Coronavirus Infections; Pneumonia

Keywords

Computed tomography; Magnetic resonance imaging; Lung MRI

Outcome Measures

Primary Outcomes (1)

• Number of zones of pulmonary parenchyma corresponding to viral pneumonia detected by chest MRI in comparison with CT scan

  Expected number - more than two zones

  Upon completion, up to 1 year

Study Arms (2)

Patients with suspected pneumonia COVID-19

Chest MRI findings: bilateral, diffuse ground-glass opacity (GGO), consolidation, "crazy paving" pattern, pleuritis.

Patients with suspected pneumonia with COVID -19

Chest CT findings: bilateral, diffuse ground-glass opacity (GGO), consolidation, "crazy paving" pattern, pleuritis.

Diagnostic Test: Chest MRI

Interventions

Chest MRI DIAGNOSTIC_TEST

Patients referred by the primary care physician with suspected pneumonia

Also known as: Chest CT scan

Patients with suspected pneumonia with COVID -19

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients with suspected viral COVID-19 pneumonia will be included in the study

You may qualify if:

• A referral from the attending physician for a chest CT scan
• Suspected pneumonia
• Signed informed consent
• Over 18 years old

You may not qualify if:

• Pregnant or nursing women
• Presence of foreign implanted objects in the body at the scan level (including cardiac pacemakers, spine metalware)

Sponsors & Collaborators

• Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department: lead

Study Sites (1)

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department

Moscow, 109029, Russia

Location

MeSH Terms

Conditions

Coronavirus Infections; Pneumonia

Condition Hierarchy (Ancestors)

Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Virus Diseases; Infections; Respiratory Tract Infections; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chief Research Officer

Study Record Dates

• First Submitted: June 5, 2020
• First Posted: June 9, 2020
• Study Start: May 19, 2020
• Primary Completion: July 19, 2021
• Study Completion: December 20, 2021
• Last Updated: March 21, 2023

Record last verified: 2023-03

Data Sharing

• IPD Sharing: Will not share

Locations

RU (1)