The Effect of Acute Phase Treatment Approaches on Creatine Kinase and the Musculoskeletal System in Different Types of Burns

NCT04417439 | Completed

• 1 other identifier: ERamazanoglu
• Study Type: observational
• Target: 37
• Locations: 1 country
• Sites: 2

Brief Summary

There are very few studies indicating the effect of acute phase treatment approaches on creatine kinase and the musculoskeletal system in the physiotherapy and rehabilitation process. Rehabilitation in burn patients is a benchmark due to return to pre-burn life. Therefore, this study was conducted to determine the effect of acute phase treatment approaches on creatine kinase and the musculoskeletal system in different types of burns.

Conditions

Burn Injury

Keywords

Acute-phase burn; Creatine Kinase, MM Form,; Musculoskeletal Development; Treatment Effectiveness

Outcome Measures

Primary Outcomes (3)

• universal goniometer

  Universal goniometer was used to measure arm flexion movement.

  three weeks

• A tape measure with a width of 7 mm

  Anthropometric measurement (arm circumference measurement) was made with a tape measure of 7 mm width.

  three weeks

• The biochemical examination of CK (creatine kinase)

  Creatine kinase concentration in the blood was evaluated.

  three weeks

Study Arms (3)

flame burns

The joint range of motion was assessed by a universal goniometer within the affected areas of burn patients. A tape measure with a width of 7 mm was used to evaluate the circumference measurement in individuals. The biochemical examination of CK (creatine kinase) was performed in the laboratories.

Other: universal goniometer. evaluate the circumference measurement. The biochemical examination of CK (creatine kinase)

scald burns

The joint range of motion was assessed by a universal goniometer within the affected areas of burn patients. A tape measure with a width of 7 mm was used to evaluate the circumference measurement in individuals. The biochemical examination of CK (creatine kinase) was performed in the laboratories.

Other: universal goniometer. evaluate the circumference measurement. The biochemical examination of CK (creatine kinase)

electrical burns

The joint range of motion was assessed by a universal goniometer within the affected areas of burn patients. A tape measure with a width of 7 mm was used to evaluate the circumference measurement in individuals. The biochemical examination of CK (creatine kinase) was performed in the laboratories.

Other: universal goniometer. evaluate the circumference measurement. The biochemical examination of CK (creatine kinase)

Interventions

universal goniometer. evaluate the circumference measurement. The biochemical examination of CK (creatine kinase) OTHER

The joint range of motion within the affected areas of burn patients was assessed by a universal goniometer. A 7-mm-wide tape measure was used to evaluate circumference measurement in individuals. The biochemical analysis of CK (creatine kinase) was performed by an expert on blood samples taken from patients in the hospital laboratories.

electrical burns; flame burns; scald burns

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

A total of 37 individuals, including 10 females and 27 males

You may qualify if:

• the study were being aged between 18-65 years and having different burn types, and flame, scald, and electrical burns were included in the study.
• The burn percentage and mortality percentage were calculated, and patients with a burn percentage of less than fifty percent were included.

You may not qualify if:

• the study were having a systemic disease, having substance abuse, and having a burn percentage of more than fifty percent.

Sponsors & Collaborators

• Inonu University: lead

Study Sites (2)

Malatya İnönü University

Malatya, 44000, Turkey (Türkiye)

Location

Turgut Özal medical center

Malatya, 44280, Turkey (Türkiye)

Location

Related Publications (2)

• Flores O, Tyack Z, Stockton K, Ware R, Paratz JD. Exercise training for improving outcomes post-burns: a systematic review and meta-analysis. Clin Rehabil. 2018 Jun;32(6):734-746. doi: 10.1177/0269215517751586. Epub 2018 Jan 10.

  PMID: 29320878 BACKGROUND

• Goverman J, Mathews K, Goldstein R, Holavanahalli R, Kowalske K, Esselman P, Gibran N, Suman O, Herndon D, Ryan CM, Schneider JC. Adult Contractures in Burn Injury: A Burn Model System National Database Study. J Burn Care Res. 2017 Jan/Feb;38(1):e328-e336. doi: 10.1097/BCR.0000000000000380.

  PMID: 27380122 BACKGROUND

MeSH Terms

Conditions

Burns

Interventions

Creatine Kinase

Condition Hierarchy (Ancestors)

Wounds and Injuries

Intervention Hierarchy (Ancestors)

Phosphotransferases (Nitrogenous Group Acceptor); Phosphotransferases; Transferases; Enzymes; Enzymes and Coenzymes

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 31, 2020
• First Posted: June 4, 2020
• Study Start: May 12, 2018
• Primary Completion: May 12, 2019
• Study Completion: May 31, 2020
• Last Updated: June 9, 2020

Record last verified: 2020-06

Locations

TU (2)