NCT04415502

Brief Summary

The purpose of the study is to determine whether plasma levels of the collagen triple helix repeat containing (CTHRC1) protein can serve as a blood-based biomarker for diagnosis of rheumatoid arthritis (RA) ,and furthermore its correlation with disease activity

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 2020

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 31, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 4, 2020

Completed
4 months until next milestone

Study Start

First participant enrolled

October 1, 2020

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2021

Completed
Last Updated

June 4, 2020

Status Verified

June 1, 2020

Enrollment Period

6 months

First QC Date

May 31, 2020

Last Update Submit

June 2, 2020

Conditions

Rheumatoid Arthritis

Outcome Measures

Primary Outcomes (2)

  • CTHRC1 in RA

    Measuring of CTHRc1 in Rheumatoid arthritis patients.

    One year

  • CTHRc1 and RA disease activity

    Correlation of CTHRc1levels with RA disease activity

    One year

Study Arms (1)

Measuring of CTHRc1 , its correlation with RAdisease activity

Measuring of CTHRc1 levels and its correlation with RA disease activity

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Measuring of CTHRc1 levels and its correlation with RA disease activity

You may qualify if:

  • patients diagnosed as RA
  • age more than 18 years

You may not qualify if:

  • other rheumatological diseases Malignancies Hepatic diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Chewick S. Infection control demand administrative support. Dimens Health Serv. 1975 Dec;52(12):40-1. No abstract available.

    PMID: 1305BACKGROUND

  • Lumholtz IB. [Nurses' drug information: therapeutic action group: benzodiazepine derivatives. 2]. Sygeplejersken. 1975 Sep 24;75(38):15. No abstract available. Danish.

    PMID: 803BACKGROUND

MeSH Terms

Conditions

Arthritis, Rheumatoid

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Central Study Contacts

Lobna Amer Araby Ahmed, Master

CONTACT

01019313530Lobnaamer20@gmail.com

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

May 31, 2020

First Posted

June 4, 2020

Study Start

October 1, 2020

Primary Completion

April 1, 2021

Study Completion

May 1, 2021

Last Updated

June 4, 2020

Record last verified: 2020-06