NCT04411017

Brief Summary

Clinical trial evaluating efficacy of bowel cleansing solutions in patients with Inflammatory Bowel Disease.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2019

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2019

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

July 24, 2019

Completed
10 months until next milestone

First Posted

Study publicly available on registry

June 1, 2020

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2021

Completed
20 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 20, 2021

Completed
Last Updated

July 23, 2021

Status Verified

May 1, 2020

Enrollment Period

2.4 years

First QC Date

July 24, 2019

Last Update Submit

July 22, 2021

Conditions

Keywords

ColonoscopyInflammatory Bowel Diseases

Outcome Measures

Primary Outcomes (1)

  • Bowel cleansing

    Boston Bowel Preparation Score (BBPS), a 10-point scale assessing bowel preparation after all cleansing maneuvers are completed by the endoscopist. Each region of the colon receives a "segment score" from 0 to 3 and these segment scores are summed for a total BBPS score ranging from 0 to 9. Therefore, the maximum BBPS score for a perfectly clean colon without any residual liquid is 9 and the minimum BBPS score for an unprepared colon is 0.

    1 year

Secondary Outcomes (2)

  • Treatment related adverse events

    1 year

  • Preparation Tolerability: total volume of solution finally taken by the patient

    1 year

Study Arms (3)

1L PEG

ACTIVE COMPARATOR
Procedure: Endoscopy

2L PEG

ACTIVE COMPARATOR
Procedure: Endoscopy

2L sodium picosulfate

ACTIVE COMPARATOR
Procedure: Endoscopy

Interventions

EndoscopyPROCEDURE

Colonoscopy

1L PEG2L PEG2L sodium picosulfate

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients between 18y and 90y
  • Patients with a diagnosis of IBD undergoing follow-up or screening colonoscopy

You may not qualify if:

  • Patients \<18y or \>90y
  • Pregnant Women
  • Patients with a past history of inadequate bowel cleansing in a colonoscopy performed in the previous 12 months prior to initiation of study
  • Patients with a history of bowel resection
  • Patients undergoing therapeutic colonoscopy
  • Patients unable to understand study protocol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Universitario La Paz

Madrid, Madrd, 28046, Spain

Location

MeSH Terms

Conditions

Inflammatory Bowel Diseases

Interventions

Endoscopy

Condition Hierarchy (Ancestors)

GastroenteritisGastrointestinal DiseasesDigestive System DiseasesIntestinal Diseases

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, SurgicalDiagnostic Techniques and ProceduresDiagnosisMinimally Invasive Surgical ProceduresSurgical Procedures, Operative

Study Officials

  • Maria Dolores Martin Arranz, PhD

    Hospital Universitario La Paz. IdiPaz. Universidad Autónoma de Madrid.

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

July 24, 2019

First Posted

June 1, 2020

Study Start

February 1, 2019

Primary Completion

June 30, 2021

Study Completion

July 20, 2021

Last Updated

July 23, 2021

Record last verified: 2020-05

Data Sharing

IPD Sharing
Will not share

Locations