NCT04410835

Brief Summary

The aim of this study is to measure current affective symptoms and psychological distress in individuals with severe mental illness during the COVID-19 pandemic using an online questionnaire survey. In addition, this study aims at identifying individual beliefs, sleep quality, attitudes concerning the virus, the adherence to the measures, believing processes, and coping strategies/resilience patterns referring to COVID-19 in different study centers.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2020

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 28, 2020

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

May 14, 2020

Completed
18 days until next milestone

First Posted

Study publicly available on registry

June 1, 2020

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2022

Completed
Last Updated

July 26, 2021

Status Verified

July 1, 2021

Enrollment Period

2 years

First QC Date

May 14, 2020

Last Update Submit

July 23, 2021

Conditions

Outcome Measures

Primary Outcomes (3)

  • Global symptom load (Anxiety, Somatisation, Depression, Global Symptom Index)

    Brief Symptom Inventory-18 with higher scores meaning a worse outcome (more depression, anxiety and somatization); Each item is weighted on a 0-4 interval scale; Minimum = 0, Maximum = 72)

    1 year

  • Depressive symptoms

    Beck Depression Inventory-II with higher scores mean a worse Outcome (more depressive Symptoms; each item is weighted on a 0-3 interval scale; Minimum = 0, Maximum = 63)

    1 year

  • Sleep disorders and Sleep Quality

    Pittsburgh Sleep Quality Index (PSQI) with higher scores mean a worse Outcome (more sleeping disturbances; Each item is weighted on a 0-3 interval scale; Minimum = 0, Maximum = 63)

    1 year

Secondary Outcomes (3)

  • Life style changes

    1 year

  • Food Craving

    1 year

  • COVID-19 associated fears and emotional responses to the pandemic

    1 year

Study Arms (2)

Psychiatric patients

Psychiatric patients with ICD-10 (International Statistical Classification of Diseases and Related Health Problems) F2/F3/F4 diagnosis

Diagnostic Test: Online Survey

Healthy Controls

Participants who do not have a psychiatric disorder or a first degree relative with psychiatric disorder.

Diagnostic Test: Online Survey

Interventions

Online SurveyDIAGNOSTIC_TEST

Psychological questionnaires

Healthy ControlsPsychiatric patients

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Based on previous experience of the researchers working within the sector, we anticipated that it would be possible to recruit a conservative average of 100 psychiatric patients per outpatient clinic Thus, we aim to recruit at least 500 patients and 500 healthy controls in total which would be a large enough sample to conduct most subgroup analyses. Nevertheless, in case we can recruit a larger number of participants allowing further subgroup analysis it would be useful. The assumed response rate is 70 %.

You may qualify if:

  • Minimum age 18 years
  • voluntary participation

You may not qualify if:

  • Subject refuses to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical University Graz, Department of Psychiatry and Psychotherapeutic Medicine

Graz, Styria, 8036, Austria

RECRUITING

MeSH Terms

Conditions

Coronavirus InfectionsMental Disorders

Condition Hierarchy (Ancestors)

Coronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsVirus DiseasesInfections

Study Officials

  • Eva Reininghaus, Prof.

    Medical University of Graz

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 14, 2020

First Posted

June 1, 2020

Study Start

April 28, 2020

Primary Completion

April 30, 2022

Study Completion

April 30, 2022

Last Updated

July 26, 2021

Record last verified: 2021-07

Locations