NCT04399850

Brief Summary

Pain during ICU stay remains one of the major complaints for patients. Beside pain intensity, well described by patients' self reports, pain distress, which is an emotional experience, cannot be treated with usual analgesia. The aim of the study is to analyze the impact of hypnosis on pain intensity and distress on short and long term outcomes in non-sedated ICU patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
124

participants targeted

Target at P75+ for not_applicable pain

Timeline
Completed

Started Sep 2020

Longer than P75 for not_applicable pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 29, 2020

Completed
23 days until next milestone

First Posted

Study publicly available on registry

May 22, 2020

Completed
4 months until next milestone

Study Start

First participant enrolled

September 28, 2020

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 28, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 28, 2024

Completed
Last Updated

July 17, 2024

Status Verified

July 1, 2024

Enrollment Period

3.5 years

First QC Date

April 29, 2020

Last Update Submit

July 15, 2024

Conditions

Keywords

invasive procedurepain distresshypnosis

Outcome Measures

Primary Outcomes (1)

  • Pain distress

    Pain distress change in the hypnosis group measured before and within the first hour after the procedure. Pain distress will be assessed using Numeric rating scale, which goes from 0 (no pain stress) to 10 (maximum pain stress).

    within the before and the first hour after the procedure

Secondary Outcomes (10)

  • Pain intensity

    within first hour and first 24 hours after procedure

  • Number of adverse events

    during procedure

  • Length of each painful procedure

    up to 3 months

  • Analgesia dose

    within first and 24 hours after procedure

  • Type of analgesia

    within first and 24 hours after procedure

  • +5 more secondary outcomes

Study Arms (2)

Patients who receive hypnosis

EXPERIMENTAL

Patients who receive hypnosis during procedure by experiment physician

Other: Hypnosis group

Control arm

NO INTERVENTION

Patient with conventional pain management

Interventions

Patients who receive hypnosis

Patients who receive hypnosis

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patients aged 18 years and older
  • ICU hospitalisation
  • Non-sedated patients who need an invasive procedure (Invasive procedures are defined as chest tube (insert or remove), fibroscopy, catheter insert, lumbar punction and bone marrow aspiration)
  • Physician experienced in hypnosis available
  • written informed consent
  • health insurance

You may not qualify if:

  • sedation and intubation, delirium, end-of-life decision,
  • deaf patient,
  • patient who does not understand French language,
  • pregnancy
  • patient under guardianship or curatorship
  • lack of health insurance

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hôpital Saint-Louis

Paris, France

Location

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 29, 2020

First Posted

May 22, 2020

Study Start

September 28, 2020

Primary Completion

March 28, 2024

Study Completion

March 28, 2024

Last Updated

July 17, 2024

Record last verified: 2024-07

Locations