NCT04399473

Brief Summary

The purpose of this observational study is understanding the underlying mechanisms of how PNE impacts disability in chronic low back pain patients (CLBP). The investigator will explore whether the PNE effect on patient disability is mediated by changes in pain catastrophizing, pain self-efficacy and patient beliefs about pain. Also, the investigator will explore whether the effect of PNE on disability is moderated by patient expectation.The observational multisite pre-post cohort study will be conducted in PT clinics in the Kingdom of Saudi Arabia (KSA).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
249

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2020

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 19, 2020

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 22, 2020

Completed
6 months until next milestone

Study Start

First participant enrolled

November 29, 2020

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2021

Completed
Last Updated

January 27, 2025

Status Verified

January 1, 2022

Enrollment Period

1.1 years

First QC Date

May 19, 2020

Last Update Submit

January 22, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Oswestry Disability Index (ODI)(Arabic version).

    Change score of disability scores from baseline.

    2 week.

Other Outcomes (4)

  • Pain Self-Efficacy (PSE).

    2 week.

  • Pain Catastrophism.

    2 week.

  • Patient Back Beliefs.

    2 week.

  • +1 more other outcomes

Study Arms (2)

Control group: Usual PT Care

Experimental group: PNE + Usual PT Care

Participants in this arm will receive PNE education in addition to Usual PT Care

Behavioral: Pain Neuroscience Education (PNE)

Interventions

Participates in the experimental group will receive 15mins X 4 sessions of pain education by the eligible trained physical therapist in addition to usual care PT treatment.

Experimental group: PNE + Usual PT Care

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with Nonspecific Chronic Low Back Pain (NCLBP)

You may qualify if:

  • Pain between the 12th rib and buttocks with or without symptoms into one or both legs which originate from the lumber region.
  • Pain \>12 weeks.
  • Oswestry disability score =\>20%.

You may not qualify if:

  • No surgery to the lumbosacral spine in the last 12 months.
  • No evidence of "Red flags" conditions (e.g., cauda equina, neurological deficits, cancer, fracture or infection).
  • Not currently receiving any intervention for LBP from other healthcare provider (e.g., physical therapy, massage therapy, etc.).
  • Not currently known to be pregnant.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

East Jeddah General Hospital-Physical Therapy Department

Jeddah, Mecca Region, 22253, Saudi Arabia

Location

King Abdulaziz Hospital-Rehabilitation Center

Jeddah, Mecca Region, 22421, Saudi Arabia

Location

King Fahad General Hospital-Physical Therapy Department

Jeddah, Mecca Region, 23325, Saudi Arabia

Location

King Abdullah Complex-Physical Therapy Department

Jeddah, Mecca Region, 23826, Saudi Arabia

Location

King Fiasal Hospital-Physical Therapy Department

Ta'if, Mecca Region, 26514, Saudi Arabia

Location

King Abdulaziz Hospital-Phyiscal Therapy Department

Ta'if, Mecca Region, 26521, Saudi Arabia

Location

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
2 Weeks
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 19, 2020

First Posted

May 22, 2020

Study Start

November 29, 2020

Primary Completion

December 30, 2021

Study Completion

December 30, 2021

Last Updated

January 27, 2025

Record last verified: 2022-01

Data Sharing

IPD Sharing
Will not share

Locations