NCT04399057

Brief Summary

the study proposes the use of a new non-invasive ultrasound method for the diagnosis of erectile dysfunction. in particular, the shear Wave elastosonosgraphy of the corpora cavernosa will be used. this last method quantitatively measures the rigidity of the analyzed tissues.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
322

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 12, 2020

Completed
1 day until next milestone

Study Start

First participant enrolled

May 13, 2020

Completed
7 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 20, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 22, 2020

Completed
9 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2020

Completed
Last Updated

May 22, 2020

Status Verified

May 1, 2020

Enrollment Period

7 days

First QC Date

May 12, 2020

Last Update Submit

May 18, 2020

Conditions

Keywords

erectile dysfunctionelastosonographypenile diseasesInternational index of erectile functionerectile hardness score

Outcome Measures

Primary Outcomes (3)

  • Shear Wave elastosonografy and Erectile tissues Stiffness.

    use of shear wave elastosonography for the diagnosis of erectile dysfunction by measuring the stiffness of the erectile tissue. the rigidity of the cavernous bodies is expressed in numerical values obtained in Kilopascals.

    15 days

  • Shear Wave Elastosonography and IIEF5 questionnaire

    comparison between the score in the International index of Erectile Function short form questionnaire (minimum value is 5 and maximum value is 25) and the stiffness values obtained by elastosonography with numerical absolute values obtained in kilopascals

    15 days

  • Shear Wave elastosonography and EHS questionnaire

    comparison between the score in the Erectile hardness Score questionnaire (minimum value is 0 an maximum value is 4) and the stiffness absolute values obtained by elastosonography with the numerical values obtained in kilopascals

    15 days

Secondary Outcomes (1)

  • cut-off value at elastosonography and erectile dysfunction

    15 days

Study Arms (1)

andrological patients

shear wave elastosonography of the corpora cavernosa was performed to all patients who went to our clinic for andrological problems. in addition, the International Index of Erectile Function short form (IIEF5) questionnaire and the Erectile Hardness Score (EHS) questionnaire were administered.

Diagnostic Test: shear Wave Elastosonography

Interventions

both the left cavernous body and the right cavernous body are ideally divided longitudinally into three sections: proximal, middle and distal. subsequently for each section of the corpora cavernosa the stiffness of the tissue is calculated by means of a specific Region Of Interest (ROI). the result is expressed in Kilopascals and in a color scale. when registering the stiffness the patient is asked to hold their breath.

andrological patients

Eligibility Criteria

Age18 Years - 80 Years
Sexmale
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

the population chosen is male, who goes to the clinics for andrological problems.

You may qualify if:

  • male who came attended our general andrology clinic between January 2019 to January 2020.

You may not qualify if:

  • with: age \>80 years or \<18 years. , 2
  • diabetes,
  • spinal trauma,
  • treatment with continuous PDE5i,
  • ischemic heart disease for less than 6 months,
  • pelvic surgery for within less than 1 year,
  • hypotestosteronemia (\<8 nmol/L),
  • La Peyronie's disease.
  • penile trauma.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Elisabetta Costantini

Terni, 05100, Italy

RECRUITING

MeSH Terms

Conditions

Erectile DysfunctionPenile Diseases

Condition Hierarchy (Ancestors)

Genital Diseases, MaleGenital DiseasesUrogenital DiseasesSexual Dysfunction, PhysiologicalMale Urogenital DiseasesSexual Dysfunctions, PsychologicalMental Disorders

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chief U.O.C. Chirurgia Urologica ad indirizzo andrologico ed Uroginecologico

Study Record Dates

First Submitted

May 12, 2020

First Posted

May 22, 2020

Study Start

May 13, 2020

Primary Completion

May 20, 2020

Study Completion

May 31, 2020

Last Updated

May 22, 2020

Record last verified: 2020-05

Data Sharing

IPD Sharing
Will not share

Locations