NCT04396951

Brief Summary

pre and post intervention quasi-experimental epidemiological study without a control group will be carried out in large burned patients that will evaluate the influence on metabolic expenditure of the inclusion of active external rewarming in the control of body temperature.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
34

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2020

Typical duration for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 6, 2020

Completed
15 days until next milestone

First Posted

Study publicly available on registry

May 21, 2020

Completed
3 months until next milestone

Study Start

First participant enrolled

September 1, 2020

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2022

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2022

Completed
Last Updated

May 21, 2020

Status Verified

May 1, 2020

Enrollment Period

1.5 years

First QC Date

May 6, 2020

Last Update Submit

May 15, 2020

Conditions

Keywords

Nursingenergy metabolismhypothermiaheatingburnsthermoregulation

Outcome Measures

Primary Outcomes (1)

  • Metabolic expenditure

    Compare the metabolic expenditure of burned patients according to the heating method between the combination of active and passive external adjusted to thermal comfort versus external passive overheating.

    Measure during 6 hours with indirect calorimetry in first recovery week with three heating methods

Secondary Outcomes (2)

  • Optimal environmental temperature

    Measure during 6 hours with three heating methods in first recovery week

  • Thermal comfort

    Measure during 6 hours with three heating methods first recovery week

Other Outcomes (1)

  • Nursing care planning

    Measure Scales during three heating methods in six hours, first recovery week

Study Arms (3)

Passive external overheating

NO INTERVENTION

Passive external overheating in the environmental temperature control adjusted to thermal comfort. Measure during 6 hours with indirect calorimetry

Active external overheating with heating plate

ACTIVE COMPARATOR

Combination of passive and active external heating with heating plate Measure during 6 hours with indirect calorimetry

Device: Active external overheating with heating plate, Aragonia ® MTC 400

Active external overheating with air blanket

ACTIVE COMPARATOR

Combination of passive and active external heating with convective air blanket Measure during 6 hours with indirect calorimetry

Device: Active external overheating with air blanket, Equator Level 1® de Smiths Medical

Interventions

It is a heating device that is adjustable in height up to 50 cm from the patient and generates radiant heat at low temperature (up to 39 ◦C) distributed evenly. It is equipped with an adjustable 0-9 potentiometer and has a skin temperature probe as a control and safety mechanism Measure during 6 hours with indirect calorimetry in first week

Also known as: Aspira Medical AB Aragonia ® MTC 400. Certificate CE 0413
Active external overheating with heating plate

Composed of a unit that produces hot air and forced air adjustable from 38ºC to 43ºC. Sends hot forced air distributed by tubular blanket that convectively heats the patient by diffusing hot air directed at the patient through the textile pore of the air blanket Measure during 6 hours with indirect calorimetry in first week

Also known as: Equator Level 1® de Smiths Medical REF EQ-5000. Certificate CE 0473
Active external overheating with air blanket

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients over 18 years of age.
  • Patients with thermal burns.
  • Patient with high burn criteria according to ABA:
  • nd degree burn
  • Patient 18 - 59 years: SCQ\> 20%
  • Patient\> 60 years or pathology: SCQ\> 10%
  • rd degree burn
  • SCQ\> 10%
  • Patients on mechanical ventilation

You may not qualify if:

  • Sepsis criteria according to ABA.
  • Enzyme debridement application (data within 24 hours).
  • hours after a surgical intervention.
  • After 2 hours after healing burns
  • Patients in hemorrhagic shock

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

BurnsHypothermia

Condition Hierarchy (Ancestors)

Wounds and InjuriesBody Temperature ChangesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Juan Manuel Alonso Fernández, MSN

    Sanidad Castilla y León

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Juan Manuel Alonso Fernández, MSN

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: A pre and post intervention quasi-experimental epidemiological study without control group, will be carried out in large burned patients that will assess the influence on the metabolic expenditure of the inclusion of active external reheating in the control of the environmental temperature.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Master of Science in Nursing

Study Record Dates

First Submitted

May 6, 2020

First Posted

May 21, 2020

Study Start

September 1, 2020

Primary Completion

March 1, 2022

Study Completion

October 1, 2022

Last Updated

May 21, 2020

Record last verified: 2020-05

Data Sharing

IPD Sharing
Will not share