Investigation of Factors Affecting Cardiorespiratory Fitness in Individuals With Systemic Hypertension

NCT04396405 | Completed

• 1 other identifier: GO 20/360
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators aim to investigate the factors affecting cardiorespiratory fitness in individuals with systemic hypertension.

Conditions

Systemic Hypertension; Muscle Weakness; Vascular Stiffness

Outcome Measures

Primary Outcomes (2)

• Exercise Capacity

  Exercise capacity assesment with six minute stepper test

  1 year

• Submaximal Exercise Capacity

  Exercise capacity assesment with six minute walk test

  1 year

Secondary Outcomes (5)

• Quality of Life assesment

  1 year

• Arterial Stiffness

  1 year

• Medication Adherence

  1 year

• Physical Activity

  1 year

• Ventricular functions ve ventricular structure

  1 year

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Stable hypertension patients between the ages of 18-65, who are in accordance with the criteria for inclusion in the clinical condition of Hacettepe University Faculty of Medicine, Department of Cardiology and Department of Nephrology from Hacettepe University Faculty of Medicine, Department of Internal Diseases, are included in the study. and who reffered to the Cardiopulmonary Rehabilitation Unit for Physiotherapy also who are willing to participate in the study will be include in the study.

You may qualify if:

• Being 18 or older,
• Having been diagnosed with primary or secondary hypertension,
• Volunteering to participate in the study,

You may not qualify if:

• Has a neurological, cognitive or orthopedic disease that will affect the measurements, Having severe respiratory disease (FEV1 \<35%; FVC \<50%),
• Presence of acute infection,
• Malignancy
• Dementia,
• Having hormone replacement therapy,
• Have had any cardiovascular events in the last 6 months,
• Body mass index is more than 40 kg / cm2,
• Ejection fraction less than 50%,
• Uncontrolled hypertension, diabetes,

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Hypertension; Muscle Weakness

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Officials

• EBRU CALIK-KUTUKCU, PhD

  Hacettepe University

  PRINCIPAL INVESTIGATOR

• LALE TOKGOZOGLU, MD

  Hacettepe University

  STUDY CHAIR

• YUSUF ZIYA SENER, MD

  Hacettepe University

  STUDY CHAIR

• TOLGA YILDIRIM, MD

  Hacettepe University

  STUDY CHAIR

• JABRAYİL JABRAYİLOV, MD

  Hacettepe University

  STUDY CHAIR

• BEYZA NUR KARADUZ, MsC

  Hacettepe University

  STUDY CHAIR

• BURCU OZCAN, MsC

  Hacettepe University

  STUDY CHAIR

• DENİZ INAL-INCE, PhD

  Hacettepe University

  STUDY CHAIR

• MELDA SAGLAM, PhD

  Hacettepe University

  STUDY CHAIR

• NACİYE VARDAR-YAGLI, PhD

  Hacettepe University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: May 8, 2020
• First Posted: May 20, 2020
• Study Start: January 15, 2021
• Primary Completion: August 31, 2021
• Study Completion: October 30, 2021
• Last Updated: July 5, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)