NCT04395261

Brief Summary

The investigators asked the question if they can better estimate the middle ear status in OME that help them to decide between early intervention or longer follow up.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
202

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2016

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2016

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2018

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

May 15, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 20, 2020

Completed
Last Updated

September 15, 2023

Status Verified

September 1, 2023

Enrollment Period

3 years

First QC Date

May 15, 2020

Last Update Submit

September 14, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Resonance frequency

    Wideband resonance frequency was measured

    The same 1 day with the operation

  • Absorbance

    Wideband absorbance of frequencies between 250-8000 Hz were measured

    The same 1 day with the operation

Study Arms (5)

Group 0

Patients were divided into groups according to observation in surgery Empty ear in operation

Diagnostic Test: Wideband Tympanometry

Group 1

Patients were divided into groups according to observation in surgery Serous fluid in operation

Diagnostic Test: Wideband Tympanometry

Group 2

Patients were divided into groups according to observation in surgery Mucoid fluid in operation

Diagnostic Test: Wideband Tympanometry

Group 3

Patients were divided into groups according to observation in surgery Adhesive tympanic membrane in operation

Diagnostic Test: Wideband Tympanometry

Group 4

Control group. Subjects with no otitis media with effusion

Diagnostic Test: Wideband Tympanometry

Interventions

Wideband TympanometryDIAGNOSTIC_TEST
Group 0Group 1Group 2Group 3Group 4

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

children with otitis media with effusion

You may qualify if:

  • All patients were diagnosed by ear examination, pneumatic otoscopy, and type B tympanogram with 226 Hz tympanometry. They were followed for 3 months with proper medication. After 3 months if there was no change with ear examination and 226 Hz tympanometry, surgical ventilation tube insertion was offered.

You may not qualify if:

  • The patients with chronic ear diseases, ototoxic drug use, neurologic disease were excluded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Otitis Media with Effusion

Condition Hierarchy (Ancestors)

Otitis MediaOtitisEar DiseasesOtorhinolaryngologic Diseases

Study Officials

  • Fazıl N Ardıç, MD

    Chief of Department

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof.Dr.

Study Record Dates

First Submitted

May 15, 2020

First Posted

May 20, 2020

Study Start

January 1, 2016

Primary Completion

December 30, 2018

Study Completion

December 30, 2018

Last Updated

September 15, 2023

Record last verified: 2023-09

Data Sharing

IPD Sharing
Will not share

Data will be available in the university depository