Lung Ultrasound Score in Covid 19 Infectious Disease in Critical Care (LUS-COVID19)

NCT04393402 | Completed

• 1 other identifier: 20reamedcovid03
• Study Type: observational
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

It might be necessary with Sars-Cov2 pneumopathy patient to repeat thoracic images, the tomodensitometry ones in particular. This task is difficult and nearly impossible for several reasons: respiratory and hemodynamic unstable patient, prone position and due to the high contagious nature of the disease. The lung ultrasound is an easy tool, fast (between 5 and 10 minutes) and as a limited training. In the context of the Sars-Cov2 epidemic, Buonsenso and al case report depict the first lung ultrasound for a Covid 19 patient. Peng and al in Intensive Care Medicine accentuate the usefulness of this particular technic. In the American Journal of Respiratory and Critical Care Medicine, a study has been published as a point-of-care, in which the doctors reported using the lung ultrasound with intensive and critical care patient. In Critical Care 2016, it has been showed that ultrasound allowed with neat precisions, to predict severe ARDS patient response to the prone position, all-cause. Another researchers team found a good correlation between lung ultrasound, the SOFA, APACHE II, CPIS score, and patient mortality. And a new applicability in the pulmonary recruitment by PEEP titration has been presented. The aim of this study is to evaluate the lung ultrasound in Covid19 ARDS.

Conditions

COVID

Outcome Measures

Primary Outcomes (1)

• LUS applicability with COVID 19

  In dorsal position, or in prone position, the two hemithorax will be subdivided in 6 parts, and a score will be attributed with the following criteria : A-Lines (0 point), \> 3 B-lines (1 point), B-Lines coalscent (2 points), and pulmonary consolidation (3 points). For the echography we can use a convexe sonde, or a "cardiac" sonde.

  10 months

Secondary Outcomes (3)

• Radiographic correlation (chest Xray and tomodensitometry)

  10 months

• LUS Mortality prediction

  10 months

• Prediction of Prone position response

  10 months

Study Arms (1)

Patients with Covid-19 and admitted in critical care unit

Procedure: lung ultrasound (LUS)

Interventions

lung ultrasound (LUS) PROCEDURE

Patients with Covid-19 Disease and admitted in critical care unit will be performed a LUS

Patients with Covid-19 and admitted in critical care unit

Eligibility Criteria

• Age: 18 Years - 95 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient with diagnose of Covid 19 by usully method, and admitted in critical care unit for oxygen-therapy or ventilatory support.

You may qualify if:

• Diagnosed Sars-Cov2 patient, with PCR method qualitative or quantitative as usual.
• Intensive or critical care admission
• ARDS with PaO2/FiO2 \<300 at the admission
• Ventilatory support or oxygen-therapy

You may not qualify if:

• Age \< 18 years-old
• Pregnancy
• Patient with tutor- or curatorship or in prison

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Nice: lead

Study Sites (1)

CHU de Nice

Nice, 06202, France

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 15, 2020
• First Posted: May 19, 2020
• Study Start: March 20, 2020
• Primary Completion: December 31, 2022
• Study Completion: December 31, 2022
• Last Updated: April 10, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)