Efficacy of Narrow Band Spectrum Endoscopy for the Diagnosis of Gastric Antral Vascular Ectasia in Patients With Liver Cirrhosis

NCT04388150 | Completed

• 1 other identifier: 0201288
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

the study aims to evaluate the role of similar technology of Narrow Band Imaging VIST video intelligent staining technology in the diagnosis of Gastric Antral Vascular ectasia in cirrhotic patients

Conditions

Gastric Antral Vascular Ectasia

Keywords

Narrow Band

Outcome Measures

Primary Outcomes (1)

• Efficacy of Narrow Band Spectrum endoscopy for the diagnosis of Gastric antral vascular ectasia in cirrhotic patients

  It is done by the new technology of VIST which is similar to Narrow Band Imaging in the diagnosis of Gastric antral vascular ectasia in cirrhotic patients that were misdiagnosed before as portal hypertension gastropathy

  it is estimated to be 12 months

Interventions

Upper gastrointestinal endoscopy and biopsy DIAGNOSTIC_TEST

Gastroscope with technology of VIST video intelligent staining technology for taking biopsies

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population includes all cirrhotic patients undergoing Upper gastrointestinal endoscopy and they have antral erosions by endoscopy

You may qualify if:

• Patients with mucosal vascular lesions at the gastric antrum suspicious of GAVE of a linear striped form or a diffuse punctate form upon conventional WLE

You may not qualify if:

• Connective tissue disorders like systemic sclerosis.
• Chronic kidney disease.
• Recent use of proton pump inhibitors in the last 14 days.
• History of gastric surgery or gastric cancer.
• Pernicious anemia.
• Recent history of non-steroidal anti-inflammatory drugs intake

Sponsors & Collaborators

• Alexandria University: lead

Study Sites (1)

Internal Medicine, Hepatology Unit. Faculty of Medicine, Alexandria University

Alexandria, Egypt

Location

Biospecimen

Retention: NONE RETAINED

biopsies

MeSH Terms

Conditions

Gastric Antral Vascular Ectasia

Interventions

Endoscopy, Digestive System; Biopsy

Condition Hierarchy (Ancestors)

Stomach Diseases; Gastrointestinal Diseases; Digestive System Diseases; Angiodysplasia; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, Digestive System; Diagnostic Techniques and Procedures; Diagnosis; Endoscopy; Diagnostic Techniques, Surgical; Digestive System Surgical Procedures; Surgical Procedures, Operative; Minimally Invasive Surgical Procedures; Cytodiagnosis; Cytological Techniques; Clinical Laboratory Techniques; Specimen Handling; Investigative Techniques

Study Officials

• Randa Salah Eldin Abdelmoneim, Master

  Alexandria University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecturer, Internal Medicine Department

Study Record Dates

• First Submitted: May 11, 2020
• First Posted: May 14, 2020
• Study Start: November 11, 2019
• Primary Completion: December 31, 2020
• Study Completion: March 1, 2021
• Last Updated: March 21, 2022

Record last verified: 2022-03

Locations

EG (1)