Open Versus Closed Wedge Distal Femoral Varus Osteotomy for the Valgus Knee. Indications, Clinical and Radiological Outcome

NCT04382118 | Completed

• 1 other identifier: 2020-00108; ch20Muendermann3
• Study Type: observational
• Target: 22
• Locations: 1 country
• Sites: 1

Brief Summary

This study is to analyze the indications of the two most popular techniques of distal femoral osteotomy (DFO) performed in patients with valgus malalignment and symptomatic degenerative changes in the lateral compartment of the knee and to evaluate the clinical and radiological outcome of a case series of patients who have received this operation at the Department of Orthopaedics and Traumatology and the Department of Surgery of the University Hospital Basel.

Conditions

Valgus Malalignment of the Knee

Keywords

Closed Wedge Distal Femoral Varus Osteotomy (CWDFO); Open Wedge Distal Femoral Varus Osteotomy (OWDFO)

Outcome Measures

Primary Outcomes (1)

• Accuracy of the correction of the deformity

  The mechanical axis of the femur and the tibia and hence the mechanical tibiofemoral angle (MFTA) will be measured pre- and postoperatively. (the goal of the operation is a neutral alignment, MFTA angle of 0°)

  at Baseline

Secondary Outcomes (3)

• incidence of disruptive hardware

  at Baseline

• pain level

  at Baseline

• pain medication intake preoperatively and at the final follow up

  at Baseline

Study Arms (2)

OWDFO: Open Wedge Distal Femoral Varus osteotomy

Other: Data collection from routine medical records

CWDFO: Closed Wedge Distal Femoral Varus osteotomy

Other: Data collection from routine medical records

Interventions

Data collection from routine medical records OTHER

Data collection from routine medical records (clinical and radiological data)

CWDFO: Closed Wedge Distal Femoral Varus osteotomy; OWDFO: Open Wedge Distal Femoral Varus osteotomy

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All patients who received a DFO for valgus knee arthritis at the Clinic of Orthopaedics and Traumatology at the University Hospital Basel between 1.1.2013 and 31.12.2017 will be included in this study.

You may qualify if:

• patients who received a distal femoral osteotomy (DFO) for valgus knee osteoarthritis between 1.1.2013 and 31.12.2017

You may not qualify if:

• Absence of informed consent
• Absence of X-Rays documenting the preoperative deformity or postoperative result

Sponsors & Collaborators

• University Hospital, Basel, Switzerland: lead

Study Sites (1)

Clinic for Orthopaedics and Traumatology, University Hospital basel

Basel, Canton of Basel-City, 4031, Switzerland

Location

Related Publications (1)

• Ismailidis P, Schmid C, Werner J, Nuesch C, Mundermann A, Pagenstert G, Egloff C. Distal femoral osteotomy for the valgus knee: indications, complications, clinical and radiological outcome. Arch Orthop Trauma Surg. 2023 Oct;143(10):6147-6157. doi: 10.1007/s00402-023-04923-w. Epub 2023 Jun 6.

  PMID: 37278744 DERIVED

Study Officials

• Annegret Muendermann, Prof. Dr. med.

  Department of Orthopaedics and Traumatology, University Hospital Basel

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 6, 2020
• First Posted: May 11, 2020
• Study Start: March 24, 2020
• Primary Completion: October 31, 2021
• Study Completion: October 31, 2021
• Last Updated: March 15, 2022

Record last verified: 2022-03

Locations

CH (1)