NCT04381351

Brief Summary

In this study, critically ill patients with highly suspected or confirmed COVID-19 will be included. Main goal is the identification of noncoding RNAs in COVID-19 associated organ dysfunction with an emphasis on acute kidney injury.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Apr 2020

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 16, 2020

Completed
21 days until next milestone

First Submitted

Initial submission to the registry

May 7, 2020

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 8, 2020

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2021

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2021

Completed
Last Updated

May 27, 2020

Status Verified

May 1, 2020

Enrollment Period

11 months

First QC Date

May 7, 2020

Last Update Submit

May 22, 2020

Conditions

COVID-19

Keywords

acute kidney injury (AKI)organ dysfunction

Outcome Measures

Primary Outcomes (1)

  • predicitive value of noncoding RNAs in COVID-19 associated organ dysfunction

    12 months

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

COVID-19 patients with critical illness on ICU.

You may qualify if:

  • COVID-19

You may not qualify if:

  • kidney transplantation
  • eGFR \< 30 ml/Min
  • dialysis within last 90 days
  • chronic dialysis
  • pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Klinik für Anästhesiologie

Düsseldorf, 40225, Germany

RECRUITING

Biospecimen

Retention: SAMPLES WITHOUT DNA

Plasma, urine

MeSH Terms

Conditions

COVID-19Acute Kidney Injury

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract DiseasesRenal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 7, 2020

First Posted

May 8, 2020

Study Start

April 16, 2020

Primary Completion

March 1, 2021

Study Completion

July 31, 2021

Last Updated

May 27, 2020

Record last verified: 2020-05

Locations

DE(1)