Analysis of Volatile Organic Compounds by Electronic Noses in Hospitalised Patients for an Infection by SARS-COV-2 (COVID-19)
VOC-COVID
1 other identifier
interventional
65
1 country
1
Brief Summary
The study of volatile organic compounds (VOCs) detected in exhaled air is an innovative research area for respiratory diseases. This analysis can be done by the technique of electronic nose, simpler and faster, which provides an idea of the general profile of the VOCs without identifying them. The VOCs in exhaled air in patients hospitalized for COVID-19 infection are analysed in this study, using electronic noses.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable covid19
Started Apr 2020
Typical duration for not_applicable covid19
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 14, 2020
CompletedFirst Submitted
Initial submission to the registry
April 28, 2020
CompletedFirst Posted
Study publicly available on registry
May 7, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2021
CompletedJanuary 27, 2022
January 1, 2022
1.1 years
April 28, 2020
January 12, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Profiles of volatile organic compounds (VOCs) in exhaled air between 2 health conditions
Comparison of variation of profiles of Volatile Organic Compounds in exhaled air from electronic noses (a set of sensors interacting with the VOCs exhaled). The analysis of the generated signal (resistance or load variations) is characteristic of the composition of VOCs), between patients who improve and patients who get worse during their hospitalisation for COVID-19 infection
1 day
Secondary Outcomes (3)
Profiles of volatile organic compounds (VOCs) in exhaled air on 1 health condition
2 weeks
Profiles of volatile organic compounds (VOCs) in exhaled air between 2 periods
4 months
Profiles of volatile organic compounds (VOCs) in exhaled air by mass spectrometry at each visit based on patient evolution status.
4 months
Study Arms (1)
Volatile Organic Compounds analysis
EXPERIMENTALVolatile Organic Compounds analysis in exhaled air in patients hospitalised for COVID-19 infection
Interventions
Volatile Organic Compounds analysis in exhaled air by electronic noses
Eligibility Criteria
You may qualify if:
- Patients infected by SARS-CoV-2 whose medical condition warrants hospitalisation (out of intensive care) for oxygen therapy less or equal to 4 l/min
- Patients must be 18 years of age or older
- Fluent in the French language
- Have signed a consent form
- Being affiliated with healthcare insurance
You may not qualify if:
- Pregnant woman
- Patient deprived of liberty by judicial or administrative decision
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Hopital Fochlead
Study Sites (1)
Hôpital Foch
Suresnes, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Hélène Salvator
Pneumology unit
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 28, 2020
First Posted
May 7, 2020
Study Start
April 14, 2020
Primary Completion
June 1, 2021
Study Completion
June 1, 2021
Last Updated
January 27, 2022
Record last verified: 2022-01