NCT04377230

Brief Summary

Patients will be randomized into 2 groups:

  • Group 60: Patients will undergo a Roux-en-Y gastric bypass with a Biliopancreatic limb length of 60cm
  • Group 100: Patients will undergo a Roux-en-Y gastric bypass with a Biliopancreatic limb length of 100cm Bone mineral density will be evaluated before surgery and 2 years after it.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P25-P50 for phase_3

Timeline
Completed

Started May 2020

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 2, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 6, 2020

Completed
1 day until next milestone

Study Start

First participant enrolled

May 7, 2020

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2022

Completed
Last Updated

May 6, 2020

Status Verified

May 1, 2020

Enrollment Period

2 years

First QC Date

May 2, 2020

Last Update Submit

May 2, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Bone mineral density

    Bone mineral density will be evealuated by absorptiometry at the level of lumbar column

    2 years after surgery

Study Arms (2)

Biliopancreatic limb 60cm

EXPERIMENTAL

Roux-en- Y gastric bypass will be performed with a biliopancreatic limb length of 60cm.

Procedure: biliopancreatic limb length of 60cm.

Biliopancreatic limb 100cm

ACTIVE COMPARATOR

Roux-en- Y gastric bypass will be performed with a biliopancreatic limb length of 100cm.

Procedure: biliopancreatic limb length of 100cm.

Interventions

Roux-en- Y gastric bypass will be performed with a biliopancreatic limb length of 60cm.

Biliopancreatic limb 60cm

Roux-en- Y gastric bypass will be performed with a biliopancreatic limb length of 100cm.

Biliopancreatic limb 100cm

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Body mass index \>40 Kg/m2
  • Body mass index \>35 Kg/m2 associated to obesity related comorbidities

You may not qualify if:

  • Bone pathologies
  • Active neoplasms
  • Disorders in calcium or vitamin D metabolism

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Bone Diseases, Metabolic

Condition Hierarchy (Ancestors)

Bone DiseasesMusculoskeletal DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Study Officials

  • Jaime Ruiz-Tovar

    Garcilaso Clinic

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Carolina LLavero Garrido

CONTACT

Gilberto Gonzalez

CONTACT

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
The radiologist evaluating bone mineral density will be blinded to the biliopancreatic limb length
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Department of Surgery

Study Record Dates

First Submitted

May 2, 2020

First Posted

May 6, 2020

Study Start

May 7, 2020

Primary Completion

May 1, 2022

Study Completion

May 1, 2022

Last Updated

May 6, 2020

Record last verified: 2020-05

Data Sharing

IPD Sharing
Will not share