NCT04376489

Brief Summary

This study aims to identify states of vulnerability for lapse, identify states of receptivity for engaging in self-regulatory activities, and investigate approaches to capitalize on states of vulnerability and receptivity to deliver real-time self-regulation prompts among smokers.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
112

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2020

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 9, 2020

Completed
4 months until next milestone

First Posted

Study publicly available on registry

May 6, 2020

Completed
4 months until next milestone

Study Start

First participant enrolled

August 27, 2020

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2023

Completed
Last Updated

October 26, 2022

Status Verified

October 1, 2022

Enrollment Period

2.3 years

First QC Date

January 9, 2020

Last Update Submit

October 24, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Biochemically Verified Smoking Abstinence

    Smoking abstinence will be completed via self-reported status from participants which are biochemically verified by either expired carbon monoxide via a breathalyzer or a cotinine sample as needed if a participant is unable to attend a visit in-person.

    Post-quit date - 6-month follow-up

Study Arms (3)

Brief cognitive/behavioral strategies

EXPERIMENTAL
Behavioral: Messages (participants experiencing negative affect & cigarettes are available)Behavioral: Messages (participants not experiencing negative affect & cigarettes are available)Behavioral: Messages (participants experiencing negative affect & cigarettes are not available)Behavioral: Messages (participants not experiencing negative affect & cigarettes are not available)

Effortful self-regulatory activities

EXPERIMENTAL
Behavioral: MoodsurfBehavioral: MeditateBehavioral: JoyBehavioral: ImagineBehavioral: Notice

No activities

NO INTERVENTION

Interventions

Participants receive messages tailored for situations when they experiencing negative affect \& cigarettes are available.

Brief cognitive/behavioral strategies

Participants receive messages tailored for situations when they cigarettes are available.

Brief cognitive/behavioral strategies

Participants receive messages tailored for situations when they experiencing negative affect.

Brief cognitive/behavioral strategies

Generic messages for situations when participants are neither experiencing negative affect nor cigarettes are available.

Brief cognitive/behavioral strategies
MoodsurfBEHAVIORAL

Smart phone app that teaches participants a mindfulness-based technique in which participant "surf" the mood.

Effortful self-regulatory activities
MeditateBEHAVIORAL

Smart phone app that teaches participants a mindfulness-based meditation designed for smoking cessation.

Effortful self-regulatory activities
JoyBEHAVIORAL

Smart phone app that teaches participants to practice breathing exercise.

Effortful self-regulatory activities
ImagineBEHAVIORAL

Smart phone app that teaches participants to use their imagination to explore and manage their thoughts and feelings.

Effortful self-regulatory activities
NoticeBEHAVIORAL

Smart phone app that teaches participants to accept their thoughts and feelings.

Effortful self-regulatory activities

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years of age or older
  • Current smoker with an average of at least 3 cigarettes/day
  • Motivated to quit within the next 30 days
  • Valid home address
  • Functioning telephone number
  • Can speak, read, and write in English
  • At least marginal health literacy (as determined by 45 or greater on REALM literacy test)

You may not qualify if:

  • Contraindication for nicotine patch
  • Current use of tobacco cessation medications or other aids (i.e. buproprion)
  • Pregnancy or lactation (as self-reported)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Utah

Salt Lake City, Utah, 84102, United States

RECRUITING

MeSH Terms

Conditions

Tobacco Smoking

Interventions

cher protein, Drosophila

Condition Hierarchy (Ancestors)

SmokingBehaviorTobacco Use

Study Officials

  • David Wetter, PhD

    University of Utah

    PRINCIPAL INVESTIGATOR
  • Inbal Nahum-Shani, PhD

    University of Michigan

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
FACTORIAL
Model Details: Micro-Randomized Trial (MRT) in the development of data-driven behavioral interventions.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 9, 2020

First Posted

May 6, 2020

Study Start

August 27, 2020

Primary Completion

January 1, 2023

Study Completion

January 1, 2023

Last Updated

October 26, 2022

Record last verified: 2022-10

Data Sharing

IPD Sharing
Will share

Data will be shared with investigators working under an institution with a Federal Wide Assurance (FWA). Before sharing data, data will be stripped of all personal identifiers and all identifying codes. Data will be deemed either sensitive or low-risk, based on our characterization of the possibility of deductive disclosure. Request for sensitive data will be vetted through an assessment of both the requestor's credentials and potential risks. Note that our risk analysis will be based on a joint consideration of the total risk based on all data products requested.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
The PIs and the research team will work to make the data available in a reasonable amount of time after its collection and following the acceptance for publication of the main findings. Rules for maintaining and distributing data of the University of Utah, the University of Michigan, and the NIH will be followed.

Locations